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9781588291530

Angiogenesis and Direct Myocardial Revascularization

by ;
  • ISBN13:

    9781588291530

  • ISBN10:

    1588291537

  • Edition: Illus.
  • Format: Hardcover
  • Copyright: 2005-05-30
  • Publisher: Humana Pr Inc

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Summary

An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.

Table of Contents

Prefacep. v
Contributorsp. ix
Color Platesp. xi
No-Option Patients: A Growing Problemp. 1
Transcriptional Regulation of Angiogenesisp. 19
Preclinical Models and Experience to Datep. 37
The Coronary Microcirculation and Angiogenesisp. 65
Local and Regional Vascular Delivery for Therapeutic Angiogenesis and Myogenesisp. 107
Imaging Angiogenesis: A Guide for Clinical Management and Therapeutic Trialsp. 143
Myocardial Angiogenesis: Protein Growth Factorsp. 185
Gene Therapy for Angiogenesis in the Treatment of Cardiovascular and Peripheral Arterial Disease
Therapeutic Angiogenesis in Peripheral Arterial Disease: Current Approaches and Future Directionsp. 245
Bone Marrow Cell Transplantation for Myocardial Regeneration and Therapeutic Angiogenesisp. 261
Transplantation of Embryonic Stem Cells for Myocardial Regeneration and Angiogenesisp. 283
Skeletal Myoblast Transplantation for Cardiac Repairp. 311
Transmyocardial Laser Revascularizationp. 329
Indexp. 349
Table of Contents provided by Publisher. All Rights Reserved.

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