Annual Review of Genomics and Human Genetics

by Lander, Eric; Page, David; Lifton, Richard

• ISBN13: 9780824337018
• ISBN10: 0824337018
• Format: Hardcover
• Copyright: 2000-10-01
• Publisher: Annual Reviews

Table of Contents

Genetics, Biology, and Disease	1	(20)
Barton Childs
David Valle
Two Centuries of Genetics: A View from Halftime	21	(20)
James F. Crow
Gene Family Evolution and Homology: Genomics Meets Phylogenetics	41	(34)
Joseph W. Thornton
Rob DeSalle
Iron Metabolism: Iron Deficiency and Iron Overload	75	(24)
Nancy C. Andrews
How Many Genes Can Make a Cell: The Minimal-Gene-Set Concept	99	(18)
Eugene V. Koonin
The Human Major Histocompatibility Complex: Lessons from the DNA Sequence	117	(22)
Stephan Beck
John Trowsdale
Genetic Screening of Newborns	139	(40)
Harvey L. Levy
Simone Albers
From the Sarcomere to the Nucleus: Role of Genetics and Signaling in Structural Heart Disease	179	(46)
R. L. Nicol
N. Frey
E. N. Olson
Estimating Allele Age	225	(26)
Montgomery Slatkin
Bruce Rannala
Bioinformatics Tools for Whole Genomes	251	(30)
David B. Searls
Trinucleotide Repeats: Mechanisms and Pathophysiology	281	(48)
C. J. Cummings
H. Y. Zoghbi
Sequence Variation in Genes and Genomic DNA: Methods for Large-Scale Analysis	329	(32)
Kalim U. Mir
Edwin M. Southern
Genetic Perspectives on Human Origins and Differentiation	361	(26)
Henry Harpending
Alan Rogers
Patterns of Genetic Variation in Mendelian and Complex Traits	387	(22)
Michael E. Zwick
David J. Cutler
Aravinda Chakravarti
DNA Helicases, Genomic Instability, and Human Genetic Disease	409	(52)
Anja J. van Brabant
Rodica Stan
Nathan A. Ellis
Williams Syndrome and Related Disorders	461	(24)
Colleen A. Morris
Carolyn B. Mervis
Public Concern About Genetics	485	(22)
Philip R. Reilly
Apolipoprotein E: Far More Than a Lipid Transport Protein	507	(32)
Robert W. Mahley
Stanley C. Rall, Jr.
Methods to Detect Selection in Populations with Applications to the Human	539
Martin Kreitman
Index
Subject Index	561