Annual Review of Pharmacology and Toxicology 2004

by Cho, Arthur K.; Blaschke, Terrence F.; Insel, Paul A.; Loh, Horace H.

• ISBN13: 9780824304447
• ISBN10: 0824304446
• Format: Hardcover
• Copyright: 2004-02-01
• Publisher: Annual Reviews

Table of Contents

Predicting Human Drug Glucuronidation Parameters: Application of In Vitro and In Silico Modeling Approaches	1	(26)
John O. Miners
Paul A. Smith
Michael J. Sorich
Ross A. McKinnon
Peter I. Mackenzie
Oxidative Stress, Toxicology, and Pharmacology of Cyp2e1	27	(16)
Andres A. Caro
Arthur I. Cederbaum
The Identification of Ligands at Orphan G-Protein Coupled Receptors	43	(24)
Alan Wise
Steven C. Jupe
Stephen Rees
Biochemical Mechanism of Nitroglycerin Action and Tolerance: Is This Old Mystery Solved?	67	(20)
Ho-Leung Fung
Developmental Neuropathology of Environmental Agents	87	(24)
Lucio G. Costa
Michael Aschner
Annabella Vitalone
Tore Syversen
Offie Porat Soldin
The Integration of Pharmacokinetics and Pharmacodynamics: Understanding Dose-Response	111	(26)
Susan M. Abdel-Rahman
Ralph E. Kauffman
Transporters and Renal Drug Elimination	137	(30)
Wooin Lee
Richard B. Kim
Identification of the Major Steps in Botulinum Toxin Action	167	(28)
Lance L. Simpson
Erbb Receptors: Directing Key Signaling Networks Throughout Life	195	(24)
Thomas Holbro
Nancy E. Hynes
Novel Angiogenic Signaling Pathways and Vascular Targets	219	(20)
Roy Bicknell
Adrian L. Harris
The Role of Oxidative Stress in Carcinogenesis	239	(30)
James E. Klaunig
Lisa M. Kamendulis
Darpp-32: An Integrator of Neurotransmission	269	(28)
Per Svenningsson
Akinori Nishi
Gilberto Fisone
Jean-Antoine Girault
Angus C. Nairn
Paul Greengard
β-Adrenergic Receptors and Regulation of Energy Expenditure: A Family Affair	297	(28)
Jacques Robidoux
Tonya L. Martin
Sheila Collins
Protein Sulfenic Acids in Redox Signaling	325	(24)
Leslie B. Poole
P. Andrew Karplus
Al Claiborne
The Role of Calpain in Oncotic Cell Death	349	(22)
Xiuli Liu
Terry Van Vleet
Rick G. Schnellmann
Voltage-Gated Sodium Channels and Hyperalgesia	371	(28)
Josephine Lai
Frank Porreca
John C. Hunter
Michael S. Gold
Neurogenesis in the Adult Brain: New Strategies for Central Nervous System Diseases	399	(24)
D. Chichung Lie
Hongjun Song
Sophia A. Colamarino
Guo-li Ming
Fred H. Gage
Muscarinic Acetylcholine Receptor Knockout Mice: Novel Phenotypes and Clinical Implications	423	(28)
Jurgen Wess
Mixed-Lineage Kinases: A Target for the Prevention of Neurodegeneration	451	(24)
Leo H. Wang
Cagri G. Besirli
Eugene M. Johnson, Jr.
Analysis of GABAA Receptor Function and Dissection of the Pharmacology of Benzodiazepines and General Anesthetics Through Mouse Genetics	475	(24)
Uwe Rudolph
Hanns Mohler
Sex Differences in Pharmacokinetics and Pharmacodynamics	499	(26)
Monica Gandhi
Francesca Aweeka
Ruth M. Greenblatt
Terrence F. Blaschke
Crf and Crf Receptors: Role in Stress Responsivity and Other Behaviors	525	(34)
Tracy L. Bale
Wylie W. Vale
Membrane Trafficking of G Protein--Coupled Receptors	559	(77)
Christopher M. Tan
Ashley E. Brady
Hilary Highfield Nickols
Qin Wang
Lee E. Limbird
Indexes
Subject Index	611	(22)
Cumulative Index of Contributing Authors, Volumes 40--44	633	(3)
Cumulative Index of Chapter Titles, Volumes 40--44	636