Anti-Angiogenic Functional and Medicinal Foods

by Losso; Jack N.

• ISBN13: 9781574444452
• ISBN10: 157444445X
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-04-05
• Publisher: CRC Press

Summary

The ability to regulate and manipulate the generation or remodeling of blood vessels is key to the successful treatment of many chronic diseases, both oncological and non-oncological. Several bioactive compounds present in human diets are now known to exert an inhibitive effect on the either the signaling or construction of new blood vessels. The identification and characterization of these anti-angiogenic molecules opens a new avenue for the research and production of functional and medicinal foods with far reaching implications for the food-based treatment of chronic degenerative disease.Drawing from an extensive list of esteemed international contributors, Anti-Angiogenic Functional and Medicinal Foods explores the history and scope of the use of conventional foods, nutraceuticals, and health products in North America, Europe, the Middle East, Asia, India, Australia, and New Zealand. Recent advancements in proteomics, genomics, and toxicogenomics give us a far more detailed picture of the molecular basis of nutrition and systems toxicology. Explaining the role of angiogenesis in various chronic diseases, individual chapters consider endothelial cell responses, the mechanism of the angiogenic cascade, and the angiogenic function involved in tumors, cardiovascular disease, inflammatory arthritis, and obesity. A collection of chapters studies specific foods and their functional bioactive compounds such as the effects of edible berry anthocyanins, various Chinese medicinal foods, dietary flavanoids, probiotics, shark cartilage, EPA and DHA, and marine polysaccharides. The book concludes with adiscussion of the challenges faced during the development and delivery of anti-angiogenic functional food products.Presenting the current research and state of the science, Anti-Angiogenic Functional and Medicinal Foods provides researchers, scientists, clinical nutritionists, and oncologists with a valuable reference to this important and growing mode of therapy.

Table of Contents

History and Scope of Functional Foods Around the World
Scope of Conventional and Functional Foods in the U.S.A	p. 1
Functional Foods, Nutraceuticals and Natural Health Products in Canada	p. 33
History and Scope of Functional Foods in Japan	p. 49
Functional Foods in India: History and Scope	p. 69
History and Scope of Functional Foods in China	p. 97
History and Current Status of Functional Foods in Korea	p. 127
Australia and New Zealand	p. 139
Prophylactic Phenolic Antioxidants in Functional Foods of Tropical Island States of the Mascarene Archipelago (Indian Ocean)	p. 149
Functional Foods in Mediterranean and Middle Eastern Countries: History, Scope and Dietary Habits	p. 177
Functional Foods in the European Union	p. 213
Functional Foods in the European Union: Main Issues and Impact on the Food Industry	p. 251
Functional Foods Legislation In Brazil	p. 275
The "Ohmics" Technologies and Functional Foods
Principles of Proteomics	p. 291
Toxicogenomics and Systems Toxicology	p. 315
Angiogenesis and Chronic Degenerative Diseases
Endothelial Cell Responses to Physiological and Pathophysiological Environments	p. 349
Angiogenic Switch: Roles of Estrogenic Compounds	p. 365
Reactive Oxygen Species and Angiogenesis	p. 389
Angiogenesis in Inflammatory Arthritis	p. 403
Angiogenesis and Cardiovascular Diseases	p. 441
Angiogenesis and Anti-Angiogenesis in Brain Tumors	p. 453
Diabetes and Angiogenesis	p. 469
Obesity and Angiogenesis	p. 499
Angiogenesis, Functional, and Medicinal Foods
Screening Functional Foods as Inhibitors of Angiogenesis Biomarkers	p. 507
Role of Edible Berry Anthocyanins in Angiogenesis	p. 527
Redox Regulation of Angiogenesis: Anti-Angiogenic Properties of Edible Berries and Its Significance in a Clinical Setting	p. 549
A Novel Nutrient Mixture Containing Ascorbic Acid, Lysine, Proline, and Green Tea Extract Inhibits Critical Parameters in Angiogenesis	p. 561
Angiogenesis and Chinese Medicinal Foods	p. 581
Disposition and Metabolism of Dietary Flavonoids	p. 593
Functional Foods: Probiotics	p. 611
Potential Anti-Cancer Effects of Shark Cartilage	p. 625
Physiological Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) - A Review	p. 635
Marine Polysaccharides and Angiogenesis: Modulation of Angiogenesis by Fucoidans	p. 651
Development and Delivery of Anti-Angiogenic Functional Food Products: Opportunities and Challenges	p. 673
Index	p. 699
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