Antibodies in Viral Infection

by Burton, Dennis R.

• ISBN13: 9783540416111
• ISBN10: 3540416110
• Format: Hardcover
• Copyright: 2001-06-01
• Publisher: Springer Verlag

Summary

Antibodies are central to vaccines and it is becoming increasingly apparent that understanding how antibodies combat viruses could be crucial in a new era of vaccine development. This book describes the state of the art in explaining the anti-viral activity of antibodies at the molecular level, with chapters from many of the leaders in the field.

Table of Contents

Antibody Interactions with Rhinovirus: Lessons for Mechanisms of Neutralization and the Role of Immunity in Viral Evolution	1	(28)
T.J. Smith
Structural Studies on Antibody Interacting with Viruses	29	(16)
E. Hewat
D. Blaas
Shape and Electrostatic Complementarity at Viral Antigen-Antibody Complexes	45	(10)
V.C. Epa
P.M. Colman
Structural Studies on Viral Escape from Antibody Neutralization	55	(10)
T. Bizebard
C. Barbey-Martin
D. Fleury
B. Gigant
B. Barrere
J.J. Skehel
M. Knossow
Affinity, Complementarity, Cooperativity, and Specificity in Antibody Recognition	65	(22)
N.S. Greenspan
Mechanisms of Virus Neutralization by Antibody	87	(22)
P.J. Klasse
Q.J. Sattentau
A Model for Neutralization of Viruses Based on Antibody Coating of the Virion Surface	109	(36)
D.R. Burton
E.O. Saphire
P.W.H.I. Parren
Antibody-Mediated Enhancement of Viral Disease	145	(26)
N.J. Sullivan
The Role of the Antibody Response in Influenza Virus Infection	171	(20)
W. Gerhard
Role of Antibodies in Controlling Alphavirus Infection of Neurons	191	(10)
D.E. Griffin
S. Ubol
P. Despres
T. Kimura
A. Byrnes
Role of Mucosal Antibodies in Viral Infections	201	(28)
H. Kato
R. Kato
K. Fujihashi
J.R. McGhee
The Role of the Complement System in Virus Infections	229	(18)
G.T. Spear
M. Hart
G.G. Olinger
F.B. Hashemi
M. Saifuddin
Intrabodies as Antiviral Agents	247	(24)
W.A. Marasco
T-Bodies as Antiviral Agents	271	(30)
N. Bitton
P. Debre
Z. Eshhar
G. Gorochov
Subject Index	301