The Antimicrobial Drugs

by Scholar, Eric M.; Pratt, William B.

• ISBN13: 9780195125290
• ISBN10: 0195125290
• Edition: 2nd
• Format: Paperback
• Copyright: 2000-05-25
• Publisher: Oxford University Press

Summary

The is the third edition of a text that surveys the drugs used to treat bacterial, fungal, prarsitic, and viral infections. This book contains comprehensive presentations of the mechanisms for both the antimicrobial actions and for the adverse clinical effects of these drugs. Completediscussions of the pharmacology are highlighted by numerous charts and tables summarizing each drug's pharmacokinetic properties and microbial susceptibility. With 3500 reference citations, The Anitmicrobial Drugs provides a complete entry into the literature, making it an invaluable resource forinfectious disease specialists, clinical pharmacists, clinical microbiologists, medical students, pharmacy students, and graduate students in pharmacology and microbiology.

Table of Contents

PART 1 PRINCIPLES OF ANTIMICROBIAL THERAPY
Determinants of Bacterial Response to Antimicrobial Agents	3	(34)
Drug Resistance	37	(14)
PART 2 DRUGS EMPLOYED IN THE TREATMENT OF BACTERIAL INFECTIONS
The Inhibitors of Cell Wall Synthesis, I	51	(30)
Mechanism of Action of the Penicillins, Cephalosporins, Vancomycin, and Other Inhibitors of Cell Wall Synthesis
The Inhibitors of Cell Wall Synthesis, II	81	(46)
Pharmacology and Adverse Effects of the Penicillins, Cephalosporins, Carbapenems, Monobactams, Vancomycin, and Bacitracin
Bactericidal Inhibitors of Protein Synthesis	127	(32)
The Aminoglycosides
Bacteriostatic Inhibitors of Protein Synthesis	159	(52)
Chloramphenicol, Macrolides, Clindamycin, Spectinomycin, Tetracyclines, and Streptogramins
The Antimetabolites	211	(23)
The Sulfonamides and Trimethoprim (Trimethoprim-Sulfamethoxazole)
Antibiotics that Affect Membrane Permeability	234	(8)
Polymyxin B, Colistin, and Gramicidin A
The Urinary Tract Antiseptics	242	(15)
Nalidixic Acid and Cinoxacin; Nitrofurantoin; Methenamine; Fosfomycin
The Fluoroquinolones	257	(23)
Drugs that Act on Mycobacteria	280	(47)
Isoniazid, Rifampin, Ethambutol, Streptomycin, and Pyrazinamide; The Second-Line Antituberculosis Drugs; Drugs Effective Against Leprosy; Drugs Effective Against the Mycobacterium avium Complex
PART 3 DRUGS EMPLOYED IN THE TREATMENT OF FUNGAL INFECTIONS
Antifungal Drugs	327	(48)
The Polyene Antibiotics, Flucytosine, Azoles, Iodide, Griseofulvin, and Topical Agents
PART 4 DRUGS EMPLOYED IN THE TREATMENT OF PARASITIC DISEASE
Chemotherapy of Malaria	375	(44)
Chemotherapy of Protozoal Diseases	419	(39)
Chemotherapy of Helminthic Diseases	458	(33)
PART 5 DRUGS EMPLOYED IN THE TREATMENT OF VIRAL INFECTIONS
Chemotherapy of Viral Infections, I	491	(59)
Drugs Used to Treat Influenza Virus Infections, Herpesvirus Infections, and Drugs with Broad-Spectrum Antiviral Activity
Chemotherapy of Infections, II	550	(37)
Antiretroviral Agents
Index	587