Antimicrobial Stewardship

by Laundy, Matthew; Gilchrist, Mark; Whitney, Laura

• ISBN13: 9780198758792
• ISBN10: 0198758790
• Edition: 1st
• Format: Paperback
• Copyright: 2016-11-01
• Publisher: Oxford University Press

Summary

Antimicrobial resistance (AMR) challenges the treatment of clinical infections. Despite the decline in infectious diseases mortality rates, infections are more difficult to eliminate or contain in the host, resulting in poorer outcomes to treatment, longer hospital inpatient stays, and increased mortality.

Written by international experts in the field and supported by the review of the available evidence, including example case studies, Antimicrobial Stewardship provides a practical how-to guide on this growing area. Divided into three sections, the first sets the scene, looking at the key problems of antimicrobial resistance. Section two examines and identifies the key components of an antimicrobial stewardship program. Finally, the book explores specialist areas of antimicrobial stewardship ranging from antimicrobial pharmacokinetics and dynamics, to near patient testing, and infection biomarkers.

Antimicrobial Stewardship will be a valuable and practical resource for infection trainees, as well as specialists from the medical, pharmacy, and nursing professions.

Author Biography

Matthew Laundy, Consultant Microbiologist, St George's University Hospitals, NHS Foundation Trust,Mark Gilchrist, Consultant Pharmacist, Imperial College Healthcare NHS Trust,Laura Whitney, Consultant Pharmacist, St George's University Hospitals NHS Foundation Trust

Matthew Laundy is a consultant microbiologist at St George's University Hospitals NHS Foundation Trust. He has a special interest in antimicrobial stewardship, OPAT, paediatric infections and medical informatics. He is a Fellow of the Royal College of Pathologists and a member of the Royal College of Paediatrics and Child Health.

Mark Gilchrist is a Consultant Pharmacist in Infectious Diseases at Imperial College Healthcare NHS Trust, and an Honorary Lecturer at Imperial College, London. Mark has a specialist interest in Outpatient Parenteral Antimicrobial Therapy (OPAT) and global antimicrobial stewardship initiatives. Mark is a past chair of UK Clinical Pharmacy Infection Network and is a spokesman for the Royal Pharmaceutical Society on Antimicrobials. In 2013 Mark was awarded Fellow of the Royal Pharmaceutical Society Faculty.

Laura Whitney is a Consultant Antimicrobial Pharmacist at St George's University Hospitals NHS Trust and an Honorary Senior Lecturer at Kingston University. Her specialist interests include; antimicrobial stewardship, management of invasive fungal infections, and the treatment and prevention of Clostridium difficile infection. Laura is a member of the Royal Pharmaceutical Society of Great Britain and is a current committee member of the UK Pharmacy Infection Network.

Table of Contents

Preface
Abbreviations
Section 1: Setting the scene and starting up:
1. The international and national challenges faced in ensuring the prudent use of antimicrobials, Susan Hopkins
2. What are the principles and goals of antimicrobial stewardship, Fiona Robb and Andrew Seaton
3. Managing behaviours: Social, cultural and psychological aspects of antibiotic prescribing and use, Esmita Charani and Gabriel Birgand
4. Implementing an Antimicrobial Stewardship Programme, Patrick Doyle
Section 2: Components of an Antimicrobial Stewardship Program
5. Managing antimicrobials on the shop floor, Antonia Scobie, Mark Gilchrist, Laura Whitney and Matthew Laundy
6. Measuring antibiotic consumption and outcomes, Hayley Wickens
7. Measuring and feeding back stewardship, Jacqueline Sneddon and Billy Malcolm
8. Information technology in antimicrobial stewardship, Matthew Laundy
Section 3: Special Areas in Antimicrobial Stewardship
9. Pharmacokinetic and Pharmacodynamic Principles of Antimicrobials, Jason Roberts and Menino Osbert Cotta
10. The Role of the Microbiology Laboratory in Antimicrobial Stewardship, Peter Riley
11. Antimicrobial Stewardship in the Immuno-Compromised Patient, Haifa Lyster
12. Antimicrobial Stewardship in the Intensive Care Setting, Jonathan Ball
13. Surgical Prophylaxis, Tamsin Oswald, Simon Jameson, Mike Reed
14. Antimicrobial Stewardship in Paediatrics, Sanjay Patel and Julia Bielicki
15. Stewardship in the primary care and long term care setting, Naomi Flemming
16. Antifungal Stewardship, Laura Whitney and Tihana Bicanic
17. Near Patient Testing and infection biomarkers, Matthew Dryden
18. Antimicrobial Stewardship in a Resource Poor Setting, Marc Mendelsohn