Antioxidants in Human Health and Disease

by Basu, T. K.; Temple, Norman J.; Garg, M.

• ISBN13: 9780851993348
• ISBN10: 0851993346
• Format: Hardcover
• Copyright: 1999-09-09
• Publisher: Cab Intl

Summary

Antioxidants play an important role in the progression of major human degenerative diseases and conditions. This book covers antioxidants and their mechanisms of action; their role in a whole array of conditions including coronary heart disease, malignant disease, diabetes, cataracts, respiratory disease, cystic fibrosis, cognitive functions, and aging; their indicators for oxidative stress; and related consumer issues. In 32 chapters contributed by world authorities in antioxidants, the volume provides a comprehensive and up-to-date survey of the field.

Table of Contents

Contributors	ix
Preface	xv
Acknowledgements	xvii
Foreword	xix
SECTION 1 Antioxidants and Their Mechanisms of Action
Nutritional Antioxidants and Disease Prevention: Mechanisms of Action	1	(14)
Dennis V. Parke
Potential Role of Antioxidant Vitamins	15	(12)
Tapan K. Basu
Immunological Role of Antioxidant Vitamins	27	(16)
Adrianne Bendich
The Effect of Antioxidants on the Production of Lipid Oxidation Products and Transfer of Free Radicals in Oxidized Lipidarotein Systems	43	(12)
Nazlin K. Howell
Suhur Saeed
Regulation of the Low-density Lipoprotein Receptor by Antioxidants	55	(16)
Sebely Pal
Christina Bursill
Cynthia D.K. Bottema
Paul D. Roach
Carotenoid and Lipid/Lipoprotein Correlates of the Susceptibility of Low-density Lipoprotein to Oxidation in Humans	71	(12)
Stephen B. Kritchevsky
Thomas A. Hughes
John Belcher
Myron Gross
Antioxidation and Evolution: Dietary Restriction; and Alterations in Molecular Processes	83	(12)
Angelo Turturro
Peter H. Duffy
Ronald W. Hart
SECTION 2 Food Factors as Antioxidants
Evaluation of the Contribution of Flavanols and Caffeine to the Anticarcinogenic Potential of Tea	95	(14)
Costas Ioannides
Antioxidant Effects of Plant Phenolic Compounds	109	(14)
Kevin D. Croft
Antioxidant Effects of Soybean Isoflavones	123	(8)
Gaoli Zheng
Shoumin Zhu
Action of Ginkgo biloba as an Antioxidant	131	(10)
Noriko Noguchi
Kimihiro Nishino
Eiichi Washio
Honglian Shi
Etsuo Niki
Whole Foods, Antioxidants and Health	141	(10)
Ted Wilson
SECTION 3 Coronary Heart Disease
Antioxidants and Their Role in Coronary Heart Disease Prevention	151	(14)
David Kritchevsky
Stephen B. Kritchevsky
Effect of Antioxidants on Atherogenesis	165	(10)
Fred A. Kummerow
Mohamedain M. Mahfouz
Qi Zhou
Flavonoids and Other Phytochemicals in Relation to Coronary Heart Disease	175	(14)
Samir Samman
Philippa M. Lyons Wall
Efi Farmakalidis
Antioxidant Vitamins and Coenzyme Q10 in the Prevention and Treatment of Coronary Artery Disease and Diabetes	189	(16)
Ram B. Singh
Shanti S. Rastogi
Mahmood Moshiri
Hemmy N. Bhagvan
Fruit, Vegetables and Antioxidants: Their Role in the Prevention of Cardiovascular and Other Diseases	205	(12)
Jayne V. Woodside
Ian S. Young
John W.G. Yarnell
SECTION 4 Malignant Disease
Antioxidants and the Prevention of Cancer	217	(18)
Peter Greenwald
Sharon S. McDonald
The Role of β-Carotene and Vitamin E in the Treatment of early Gastric Premalignant Lesions: Biochemical and Clinical Aspects	235	(14)
Yuriy V. Bukin
Vladimir A. Draudin-Krylenko
SECTION 5 Other Diseases
Oxidative Stress, Vitamin E and Diabetes	249	(10)
Sushil K. Jain
An Investigation of in Vivo Antioxidant Status and v DNA Damage in Patients with IDDM	259	(12)
Mary Hannon-Fletcher
Ciara Hughes
Maurice J. O'Kane
Kenneth W. Moles
Christopher R. Barnett
Yvonne A. Barnett
Nutrition and the Risk for Cataract	271	(14)
Allen Taylor
Paul Jacques
Esther Epstein
Reactive Oxygen Species and Age-related Macular Degeneration	285	(8)
Ravindra Nath
Amod Gupta
Rajendra Prasad
Surinder S. Pandav
Rajinder Kumar
Antioxidants and Respiratory Disease	293	(20)
Ian S. Young
Heather E. Roxborough
Jayne V. Woodside
Oxidative Stress and Antioxidants in Cystic Fibrosis	313	(22)
Lisa Wood
Clare Collins
Manohar Garg
The Influence of Antioxidants on Cognitive Decline in the Elderly	335	(16)
Walter J. Perrig
Pasqualina Perrig
Hannes B. Stahelin
Schizophrenia: Role of Oxidative Stress and Essential Fatty Acids	351	(16)
Ravinder Reddy
Jeffrey K. Yao
β-Amyloid and Oxidative Stress in the Pathogenesis of Alzheimer's Disease	367	(26)
Ralph N. Martins
Chin Wern Chan
Emma Waddington
Gerald Treurink
Simon Laws
Kevin Croft
A.M. Dharmarajan
SECTION 6 Indicators of Oxidative Stress
Isoprostanes: Indicators of Oxidative Stress tn Vivo and Their Biological Activity	393	(18)
P. Quaggiotto
Manohar L. Garg
Indicators of Oxidative Stress, Antioxidants and Human Health	411	(12)
Maria Dusinska
Jan Lietava
Begona Olmedilla
Katarina Raslova
Susan Southon
Andrew R. Collins
SECTION 7 Consumer Issues
Consumer Issues in Relation to Antioxidants	423	(14)
Efi Farmakalidis
Index	437