The Art, Science, and Technology of Pharmaceutical Compounding

by Allen, Loyd V.

• ISBN13: 9781582120355
• ISBN10: 1582120358
• Edition: 2nd
• Format: Paperback
• Copyright: 2002-07-01
• Publisher: APhA Publications

Summary

Presents all the information a pharmacy student needs to understand the purpose and processes of compounding in a logical and progressive format. This comprehensive reference provides practitioners with essential information on establishing, equipping, and operating a compounding facility. Over 200 formulations cover all the dosage forms and delivery systems of modern medications. Written by eminent experts, 25 chapters discuss all aspects of good manufacturing practices, and emphasizes quality control measures for all aspects of compounding medications.

Table of Contents

Sample Formulations	vii
Preface to Second Edition	xiii
Preface to First Edition	xv
Introduction	xix
Abbreviations and Approximate Solubility Descriptors	xxv
Guidelines for Compounding Practices	1	(16)
Facilities, Equipment, and Supplies	17	(16)
Records and Record Keeping	33	(10)
Stability of Compounded Products	43	(10)
Pharmaceutical Compounding Calculations	53	(24)
Quality Control	77	(16)
Flavors, Sweeteners, and Colors	93	(12)
Preservation, Sterilization, and Depyrogenation	105	(12)
Powders and Granules	117	(16)
Capsules	133	(28)
Tablets	161	(10)
Lozenges/Troches	171	(18)
Suppositories	189	(24)
Sticks	213	(18)
Solutions	231	(18)
Suspensions	249	(14)
Emulsions	263	(14)
Ointments, Creams, and Pastes	277	(24)
Gels	301	(24)
Ophthalmic, Otic, and Nasal Preparations	325	(28)
Inhalation Products	353	(12)
Parenteral Preparations	365	(28)
Biotechnology Preparations	393	(8)
Compounding for Special Populations and Special Products	401	(14)
Veterinary Pharmaceutical Compounding	415	(30)
Appendix I Agents Withdrawn by FDA Because of Safety/Efficacy Concerns	445	(10)
Appendix II Specific Gravity Values	455	(2)
Appendix III Sodium Chloride Equivalent Values of Selected Agents	457	(10)
Appendix IV Buffers and Buffer Solutions	467	(6)
Appendix V Viscosity-Increasing Agents for Aqueous Systems	473	(4)
Index	477