Ashgate Handbook of Anti-Infective Agents

by Milne, G. W. A.

• ISBN13: 9780566083853
• ISBN10: 056608385X
• Edition: 1st
• Format: Hardcover
• Copyright: 2000-10-01
• Publisher: WILEY

Summary

The discovery, in the 1930s and 1940s, of antibiotics revolutionized the practice of medicine. Beginning with the streptomycins and the penicillins, hundreds of antibiotics have been developed and have come into routine use for the management of infectious diseases, opportunistic infections and infections resulting from trauma. This cornucopia of anti-infective agents has created a number of problems, not the least of which is the organization of information concerning them.ThisHandbook contains records for all the major drugs currently used in the treatment of infection. Monographs are provided for 1600 anti-infective agents. For each main entry, the following information is provided: the chemical name and a list of proprietary names and synonyms; the Chemical Abstracts Service (CAS) Registry Number; the European Inventory of Existing Commercial Chemical Substances (EINECS) number; and theMerck Index (12th edition) number. The physical properties of each compound are described and the known biological activity and indicated applications are presented. The structure of each compound is provided, together with a summary of the acute toxicity data associated with it, and the manufacturers and suppliers of the drug are also given. Indexes, including a master index of names and synonyms, are appended.

Author Biography

G.W.A. Milne was a Senior Researcher at the National Institutes of Health in Bethesda, MD, USA for 35 years where he worked on the use of spectroscopy for structure determination of organic compounds, and on molecular modeling in the design of drugs for the treatment of cancer and AIDS. He has been active for many years in the fields of chemical information and chemical computation and is the Editor of the American Chemical Society’s Journal of Chemical Information and Computer Science; Gardner’s Chemical Synonyms and Trade Names, Eleventh Edition (Ashgate); and Drugs: Synonyms and Properties (Ashgate).

Table of Contents

Preface	vii
Acknowledgements	ix
How to Use This Book	xi
Glossary of Units	xv
Abbreviations and Symbols	xvii
PART I MAIN ENTRIES	1	(298)
Anthelmintics	3	(16)
Antiamebics	19	(10)
Antibiotics	29	(161)
2,4-Diaminopyrimidine	29	(2)
Aminoglycoside	31	(13)
Amphenicol	44	(2)
Ansamycin	46	(1)
beta-Lactam	47	(60)
Leprostatic	107	(2)
Lincosamide	109	(2)
Macrolide	111	(8)
Nitrofuran	119	(5)
Other	124	(10)
Polypeptide	134	(9)
Quinolone	143	(9)
Sulfonamide	152	(16)
Sulfone	168	(3)
Tetracycline	171	(8)
Tuberculostatic	179	(11)
Antibacterial Adjuncts	190	(2)
Antifungals	192	(29)
Antimalarials	221	(10)
Antipneumocystic Agents	231	(1)
Antiprotozoals	232	(14)
Antirickettsials	246	(3)
Antiseptics	249	(27)
Antisyphilitics	276	(3)
Antivirals	279	(20)
PART II INDEXES	299	(138)
CAS Registry Number Index	301	(18)
Einecs Number Index	319	(10)
Name and Synonym Index	329	(108)
PART III MANUFACTURERS AND SUPPLIERS DIRECTORY	437