Assisted Reproductive Technology: Accomplishments and New Horizons

by Edited by Christopher J. De Jonge , Christopher L. R. Barratt

• ISBN13: 9780521801218
• ISBN10: 0521801214
• Format: Hardcover
• Copyright: 2002-08-19
• Publisher: Cambridge University Press

Summary

This insightful and thought-provoking collection of chapters describes the rapid advances that have revolutionized reproductive medicine. From oogenesis and spermatogenesis, through to fertilization, embryogenesis, and cloning, this volume looks at cutting-edge technologies and scientific advances. Subsequent chapters focus on infertility and its diagnosis and treatment using the full armory of assisted reproductive technologies. A concluding section surveys the impact of these developments on the provision, regulation, and financing of reproductive health care in the global community.

Table of Contents

List of contributors	ix
Foreword	xiii
Part I the gametes: present and future
Spermatogenesis in vitro in mammals	3	(23)
Bernard Jegou
Charles Pineau
Jorma Toppari
The spermatozoon as a machine: compartmentalized pathways bridge cellular structure and function	26	(14)
Alexander J. Travis
Gregory S. Kopf
Attributes of fertile spermatozoa	40	(21)
Christopher De Jonge
Christopher L. R. Barratt
In vitro oogenesis	61	(9)
Frank L. Barnes
The oocyte as a machine	70	(11)
Kate Hardy
Follicular influences on oocyte and embryo competence	81	(25)
Jonathan van Blerkom
Unresolved and basic problems in assisted reproductive technology	106	(21)
Jim Cummins
Part II Techniques: present and future
Influences of culture media on embryo development	127	(17)
Barry Bavister
Jay Baltz
Cryopreservation of immature and mature gametes	144	(23)
John K. Critser
Yuksel Agca
Erik J. Woods
Embryonic stem cells	167	(11)
Ann M. Lawler
John D. Gearhart
Modification of the male genome by gene and spermatogonial transplantation	178	(8)
Peter J. Donovan
Michael D. Griswold
late Lonnie D. Russell
Genetic diagnosis: the future	186	(20)
David Cram
David de Kretser
Cloning mammals	206	(11)
Don P. Wolf
Shoukhrat Mitalipov
Fluorescence imaging: gamete selection and intracellular sperm injection	217	(14)
Laura Hewitson
Cal Simerly
Gerald Schatten
Part III The clinic
Diagnosis and treatment of male infertility	231	(24)
Axel Kamischke
Eberhard Nieschlag
Tests of male fertility	255	(17)
R. John Aitken
Diagnosis and treatment for female subfertility	272	(10)
Peter Platteau
Paul Devroey
Ultrasound imaging at the beginning of the second millennium	282	(20)
Richard P. Dickey
Ellen Matulich
The natural and the stimulated cycle	302	(9)
Ian D. Cooke
Embryo stage and transfer number	311	(9)
Alan Trounson
The federal research base in the USA for assisted reproductive technology	320	(9)
Donna L. Vogel
Part IV Concepts for the global community
From conception to contraception	329	(26)
Gustavo F. Doncel
Christine Mauck
Douglas S. Colvard
Lourens J. D. Zaneveld
Developing immunocontraceptives	355	(11)
Eileen A. McLaughlin
Michael K. Holland
ARTistic licence: should assisted reproductive technologies be regulated?	366	(10)
Nanette R. Elster
Finances and access to assisted reproductive technologies: justice and publication of results	376	(8)
Francoise Shenfield
Sex selection	384	(13)
Joe Leigh Simpson
Sandra Ann Carson
Intracytoplasmic sperm injection: a time bomb?	397	(10)
Herman J. Tournaye
Andre C. Van Steirteghem
Cryopreservation of gametes and embryos: legal and ethical aspects	407	(8)
Susan M. Avery
Peter R. Brinsden
Index	415