Asymmetric Synthesis The Essentials

by Christmann, Mathias; Brä; se, Stefan

• ISBN13: 9783527320936
• ISBN10: 3527320938
• Edition: 2nd
• Format: Paperback
• Copyright: 2007-11-28
• Publisher: Wiley-VCH

Summary

A veritable "Who's who" of asymmetric synthesis introduces the reader to the leaders in the field with a four-page concentrate of their area of research along with a short biography. The book is organized into five chapters, each with an introductory preface. Starting from the key concepts of asymmetric synthesis diastereoselective methods, asymmetric catalysis) the focus then shifts to its application to the synthesis natural products and industrial processes. Graduate students, academic and industrial researchers will find this book a rich source of inspiration for their own work as well as an indispensable tool for the preparation of seminars and exams. A must for everyone in the field.

Author Biography

Stefan Braese is a young and successful researcher, working at the University of Karlsruhe. He has published nearly 100 publications and is recipient of the ORCHEM award in 2000.

Mathias Christmann is currently working as assistant professor at the university of Aachen.

Table of Contents

Foreword

Message from the Editors

List of Abbreviations

Named and Unnamed Reactions

List of Contributors

Chiral Auxiliaries in Asymmetric Synthesis

Introductory Chapter

Asymmetric Epoxidation of Pentadienols

Asymmetric Synthesis using Sulfur-Nitrogen Reagents

Asymmetric Syntheses with SAMP-/RAMP-Hydrazones

Asymmetric Allylation Reactions

Carbohydrates as Chiral Auxiliaries

The Use of Chiral Oxazolines in early C-C Bond Forming Reactions

Asymmetric Synthesis of Amines and Amino Acids from Amines

Metal-catalyzed Asymmetric Synthesi

Introductory Chapter

Catalytic Asymmetric Sulfur Ylide Mediated Epoxidation of Carbonyl Compounds

Asymmetric Baeyer-Villiger Reactions

Planar Chiral Ligands Based on [2.2]Paracyclophanes

Asymmetric Syntheses of 3-(trans-2-Nitrocyclopropyl)alanine and 3-(trans-2-Aminocyclopropyl)alanine

Copper-Bis(oxazoline) Catalyzed Synthesis of b-Lactams - Enantioselective Reaction of Alkynes with Nitrones

Catalytic Asymmetric Conjugate Addition Reactions of Organometallic Reagents

Catalytic Asymmetric Synthesis of Allylic Alcohols via Dynamic Kinetic Resolution

Asymmetric Cross-coupling Reactions

Asymmetric Allylic Substitutions

Asymmetric Homoaldol Reactions

Asymmetric Vinylogous Mukaiyama Aldol Reaction

Chiral Lewis Acid Catalysis in Aqueous Media

Asymmetric Epoxidation of Non-activated Olefins

Chiral Carbonyl Lewis Acid Complexes in Asymmetric Syntheses

ZACA Reaction: Zr-catalyzed Asymmetric Carboalumination of Alkenes

Bisoxazolines - a Privileged Ligand Class for Asymmetric Catalysis

Enantioselective Cycloaddition Reactions Catalyzed by Hydrogen Bonding

Direct Catalytic Asymmetric Aldol-Tishchenko Reaction

Asymmetric Heck and other Palladium-catalyzed Reactions

Asymmetric Catalysis with Chiral Acid

Biocatalysis and Organocatalysis: Asymmetric Synthesis Inspired by Nature

Introductory Chapter

Enantioselective Photochemical Reactions

Asymmetric Catalysis via Dynamic Kinetic Resolution

Catalytic Asymmetric Epoxidation of Enones and Related Compounds

Kinetic Investigations of the Soai Autocatalytic Reaction

Planar-chiral Heterocycles as Enantioselective Organocatalysts

An Organocatalytic Approach to Optically Active Six-

Table of Contents provided by Publisher. All Rights Reserved.