Summary

The traditional agents for controlling the levels of glucose in the blood remain important therapies but they have their downside from the point of view of tolerability and side effects. Moreover, they appear not to be able to counter the natural history deterioration of the disease in terms of the onset of diabetic-related complications. Recent years have seen an influx of new treatment therapies and technologies aimed at achieving better glycaemic control for diabetic patients such as liraglutide (Novo Nordisk) and saxagliptin (BMS/Astra-Zeneca) and insulin pumps, away from the more traditional therapies used (classic insulin therapy, oral hypoglycaemics). This book outlines these new technologies/treatments by collating the best journal articles published in the last year, and providing expert analysis on each one. Advanced Technologies and Treatment for Diabetes 3E brings together and critically analyses the last year's most important articles published in the world's leading medical journals on this topic. Chapters are focused on the most current hot topic areas such as: new methods of insulin delivery; internet and IT use in treatment of diabetes; bariatric surgery & diabetes; and immunotherapy for type 1 diabetes. Each chapter includes abstracts of the published articles, scientific conclusions made, as well as annotations and a comments and analysis section from the relevant chapter editor, each of which being a well-known expert in the field. All researchers in the fields of diabetes, endocrinology and metabolism will find this book extremely useful, as will diabetes technology developers, and specialist endocrinologists involved with the care of diabetic patients.

Author Biography

Prof. Moshe Phillip, Director, The Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel.
Vice Dean for Research and Development, Sackler Faculty of Medicine, Tel-Aviv University, Israel.

Prof. Dr. Tadej Battelino, Head of Department of Pediatric Endocrinology, Diabetes and Metabolism , University Children's Hospital , Ljubljana, Slovenia.
Tadej Battelino is professor of pediatrics at the Ljubljana Medical Faculty, and head of pediatric endocrinology, diabetes and metabolism at the University Children’s Hospital Ljubljana, Slovenia. He has participated as principal investigator in the CPT trial sponsored by the European Association for the Study of Diabetes, and is involved in many other international clinical and basic research projects. He has published more than 180 papers, of which 51 are published in SCI listed international journals, and is a member of many international societies, including ESPE, EASD, ISPAD. He has been an invited lecturer in Vienna and Tel Aviv Universities, and at many international meetings and symposia.

List of Contributors, vii

Preface, xvii

1 Self-Monitoring of Blood Glucose, 1
Satish K. Garg and Irl B. Hirsch

2 Continuous Glucose Monitoring in 2011, 21
Tadej Battelino and Bruce W. Bode

3 Insulin Pumps, 42
John C. Pickup

4 Closing the Loop, 56
Eyal Dassau, Christian Lowe, Cameron Barr, Eran Atlas and Moshe Phillip

5 New Insulins and Insulin Therapy, 83
Thomas Danne and Jan Bolinder

6 New Ways of Insulin Delivery, 96
Lutz Heinemann

7 Using Health Information Technology to Prevent and Treat Diabetes, 109
Neal Kaufman

8 Technology and Pregnancy, 136
Lois Jovanovic, Nicole A. Sitkin, Jennifer K. Beckerman and Moshe Hod

9 Type 1 Diabetes Mellitus: Immune Intervention, 157
Jay S. Skyler

10 Advances in Exercise, Physical Activity and Diabetes Mellitus, 174
Howard Zisser, Mark Sueyoshi, Kelsey Krigstein, Andrei Szigiato and Michael C. Riddell

11 Diabetes Technology and Treatment in the Paediatric Age Group, 203
Shlomit Shalitin and H. Peter Chase

12 Diabetes Technology and the Human Factor, 225
Alon Liberman, Bruce Buckingham and Moshe Phillip

13 New Medications for the Treatment of Diabetes, 243
Satish K. Garg and Jay S. Skyler

Index, 271

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