Autism A Neurological Disorder of Early Brain Development

by Tuchman, Roberto; Rapin, Isabelle

• ISBN13: 9781898683490
• ISBN10: 1898683492
• Edition: 1st
• Format: Hardcover
• Copyright: 2006-06-09
• Publisher: Mac Keith Press

Summary

Written by child neurologists, this comprehensive, multi-authored volume on autism systematically discusses the classification, epidemiology and neurobiology of autism. Autism lacks a unique etiology or specific pathology, so the behaviorally defined social deficits, language impairments and repetitive behaviors that define autism are explored from a developmental neurology perspective. The evidence suggesting that autism is a disorder of neuronal development is reviewed by experts on the genetics, neuroanatomy and neuroradiology, neurochemistry, immunology, and neurophysiology of autism. Chapters provide comprehensive reviews of the common neurological problems associated with autism such as epilepsy, sleep disturbances and motor and sensory deficits. Neuropsychological assessment, medical and psychopharmacologic management, educational and behavioral interventions, and outcome are discussed within the clinical content of the practising neurologist. The research agenda needed to understand the neurology of autism is emphasized throughout the book and in the conclusion.

Author Biography

Roberto Tuchman and Isabelle Rapin are the authors of Autism: A Neurological Disorder of Early Brain Development, published by Wiley.

Table of Contents

Authors' Appointments	p. vii
Foreword	p. xi
Dedication and Acknowledgments	p. xii
Preface	p. xiii
Where We Are: Overview and Definitions	p. 1
Epidemiology of Autism Spectrum Disorders	p. 19
The Social Deficit in Autism	p. 38
Language and Communication: Clinical Assessment and Differential Diagnosis	p. 51
Stereotypies and Repetitive Behaviors: Clinical Assessment and Brain Basis	p. 68
Neurobiology of Autism	p. 79
Genetic Aspects of Autism	p. 93
Neuroanatomy and Imaging Studies	p. 115
Neuroimmunology and Neurotransmitters in Autism	p. 141
Electrophysiology and Epilepsy in Autism	p. 160
Autism, Epilepsy and Eeg Epileptiform Activity	p. 174
Sleep and Autism Spectrum Disorders	p. 189
Atypical Sensory/Perceptual Responsiveness	p. 202
Motor Deficits in Autism	p. 231
Pathophysiology of Autism; Evaluation of Sleep and Locomotion	p. 248
Neuropsychological Assessment: Basic Concepts and Clinical Utility	p. 265
Treatment Approaches for the Autism Spectrum Disorders	p. 281
Outcomes of Children with Autism	p. 308
What We Have Learned, Where We Need To Go	p. 322
Index	p. 332
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