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9783527345076

Automated Sample Preparation Methods for GC-MS and LC-MS

by
  • ISBN13:

    9783527345076

  • ISBN10:

    3527345078

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2022-02-22
  • Publisher: Wiley-VCH

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Summary

An essential guide to the proven automated sample preparation process

While the measurement step in sample preparation is automated, the sample handling step is manual and all too often open to risk and errors. The manual process is of concern for accessing data quality as well as producing limited reproducibility and comparability.

Handbook of Automated Sample Preparation for CG-MS and LC-MS explores the advantages of implementing automated sample preparation during the handling phase for CG-MS and LC-MS. The author, a noted expert on the topic, includes information on the proven workflows that can be put in place for many routine and regulated analytical methods.

This book offers a guide to automated workflows for both on-line and off-line sample preparation. This process has proven to deliver consistent and comparable data quality, increased sample amounts, and improved cost efficiency. In addition, the process follows Standard Operation Procedures that are essential for audited laboratories. This important book:

  • Provides the information and tools needed for the implementation of instrumental sample preparation workflows
  • Offers proven and detailed examples that can be adapted in analytical laboratories
  • Shows how automated sample preparation can reduce cost per sample, increase sample amounts, and produce faster results
  • Includes illustrative examples from various fields such as chemistry to food safety and pharmaceuticals

Written for personnel in analytical industry, pharmaceutical, and medical laboratories, Handbook of Automated Sample Preparation for CG-MS and LC-MS offers the much-needed tools for implementing the automated sample preparation for analytical laboratories.

Author Biography

Hans-Joachim Hübschmann graduated as Certified Food Chemist from the Technical University in Berlin, Germany, working on residue analysis of anabolic agents and pesticides in foods. He started his career in diagnostics, medical analytical instruments and application development working for a number of German companies in chromatography, mass spectrometry and in biotechnology. He joined Thermo Fisher Scientific in Bremen, Germany, and held several international positions covering inorganic and isotope ratio mass spectrometry specializing in food safety, forensic and dioxin analysis. In 2015 he established the independent consulting agency HANS Analytical Solutions for the development of automated sample preparation workflows. In his current capacity he is located in Osaka, Japan, as the Vice President Sales of CTC Analytics for the emerging Asia/Pacific region.

Table of Contents

ANALYTICAL ASPECTS
Laboratory Logistics
Analytical Benefits
Standard Operation Procedure
Commercial Aspects
Workflow concepts
Sample Workflow Design
Sample Processing
Instrumental Concepts
Sample Delivery
Operational Aspects
Sample Handling
Extraction -
Clean-up
Filtration
Concentration
Derivatization
Heating -
Cooling
Mixing
Consumables

ANALYTICAL SOLUTIONS
Dilution
Regulated Methods
Volatiles
Residual solvents
Semi-volatiles
Phthalates
Polyaromatic Hydrocarbons
MCPD
FAMEs
Pesticides Extract clean-up
Drugs
Metabolomics
PFOS/PFOA
MOSH/MOAH
Magnetic beads
Doping steroids
Flavors
Pheromones
On-line water
Warfare agents
Shale aldehydes

MAINTENANCE
Syringes
Pipettes
Hardware

APPENDIX
Glossary
Solvent compatibility chart
Syringe gauge chart
Syringe needle styles

Supplemental Materials

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

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