Basic Immunology: Functions and Disorders of the Immune System (Book with Access Code)

by Abbas, Abul K.; Lichtman, Andrew H.; Pillai, Shiv

• ISBN13: 9781455707072
• ISBN10: 1455707074
• Edition: 4th
• Format: Paperback
• Copyright: 2012-11-13
• Publisher: Elsevier Science Health Science

Summary

Here's a readable and concise introduction to the workings of the human immune system, with emphasis on clinical relevance. The format makes learning easy with short, easy-to-read chapters, color tables, key point summaries, and review questions in every chapter. Relates basic science to clinical disorders through clinical cases for better application in a real-world setting. Includes a full Glossary to keep you on the cutting edge of immunologic terminology. Includes appendices summarizing the features of CD Molecules, a handy Glossary, and Clinical Cases that test your understanding of how the immune system functions in health and disease. Illustrated with beautiful full-color artwork for enhanced visual learning. Provides the most up-to-date immunology information including coverage of regulatory T cells, and biology of the Th17 subset of CD4+ T cells to keep you completely current. Access integration links through included STUDENT CONSULT access for more in-depth study.

Table of Contents

Introduction to the Immune System	p. 1
Nomenclature, General Properties, and Components
Innate Immunity	p. 23
The Early Defense Against Infections
Antigen Capture and Presentation to Lymphocytes	p. 49
What Lymphocytes See
Antigen Recognition in the Adaptive Immune System	p. 71
Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires
T Cell-Mediated Immunity	p. 93
Activation of T Lymphocytes by Cell-Associated Antigens
Effector Mechanisms of T Cell-Mediated Immunity	p. 117
Functions of T Cells in Host Defense
Humoral Immune Responses	p. 131
Activation of B Lymphocytes and Production of Antibodies
Effector Mechanisms of Humoral Immunity	p. 151
Elimination of Extracellular Microbes and Toxins
Immunological Tolerance and Autoimmunity	p. 171
Self-Nonself Discrimination in the Immune System and Its Failure
Immune Responses against Tumors and Transplants	p. 189
Immunity to Noninfectious Transformed and Foreign Cells
Hypersensitivity	p. 207
Disorders Caused by Immune Responses
Congenital and Acquired Immunodeficiencies	p. 225
Diseases Caused by Defective Immune Responses
Suggested Readings	p. 241
Glossary	p. 247
Major Cytokines	p. 283
Principal Features of Select CD Molecules	p. 287
Clinical Cases	p. 295
Index	p. 307
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