Benign by Design Alternative Synthetic Design for Pollution Prevention

by Anastas, Paul T.; Farris, Carol A.

• ISBN13: 9780841230538
• ISBN10: 0841230536
• Format: Hardcover
• Copyright: 1994-05-05
• Publisher: American Chemical Society

Summary

Describes the current status and potential of synthetic chemistry designed to use and to generate fewer hazardous substances. Examines new techniques for carrying out transformations in environmentally benign solvent systems. Presents research results on the replacement of hazardous feedstocks with biologically derived, innocuous feedstocks; of hazardous reagents with visible light; and of phosgene, benzene, and halogens in a variety of industrially important reactions. Provides examples of how alternative synthetic design for pollution prevention has been made commercially viable. Describes how to conduct a source-reduction assessment and analyzes computer-assisted synthetic design.

Table of Contents

Preface

In Memoriam

Overview

Benign by Design Chemistry

Environmentally Benign Chemical Synthesis and Pro for the Economy and the Environment

Benign Chemistry: Research

Microbial Biocatalysis: Synthesis of Adipic Acid from D-Glucose

Mechanistic Study of a Catalytic Process for Carbonylation of Nitroaromatic Compounds: Developing Alternatives for Use of Phosgene

Preparative Reactions Using Visible Light: High Yields from Pseudoelectrochemical Transformation

A Photochemical Alternative to the Friedel-Crafts Reaction

Mn(III)-Mediated Electrochemical Oxidative Free-Radical Cyclizations

Supercritical Carbon Dioxide as a Medium for Conducting Free-Radical Reactions

The University of California-Los Angeles Styrene Process

Benign Chemistry: Industrial Applications

Generation of Urethanes and Isocyanates from Amines and Carbon Dioxide

Nucleophilic Aromatic Substitution for Hydrogen: New Halide-Free Routes for Production of Aromatic Amines

Chemistry and Catalysis: Keys to Environmentally Safer Processes

Tools for Assessment of Benign Chemistry

Alternative Syntheses and Other Source Reduction Opportunities for Premanufacture Notification Substances at the U.S. Environmental Protection Agency

Computer-Assisted Alternative Synthetic Design for Pollution Prevention at the U.S. Environmental Protection Agency

Indexes

Author Index

Affiliation Index

Subject Index

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