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9780879697365

Binding and Kinetics for Molecular Biologists

by ;
  • ISBN13:

    9780879697365

  • ISBN10:

    0879697369

  • Edition: 1st
  • Format: Spiral Bound
  • Copyright: 2006-11-28
  • Publisher: Cold Spring Harbor Laboratory Press
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List Price: $65.07

Summary

This handbook offers a practical guide to the principles of quantitative analysis in biological experiments. The material is primarily aimed at working molecular biologists, but the scope and clarity of presentation make it equally suitable as an introduction for students. Topics covered range from the basics #x14; such as measuring the concentrations of macromolecules #x14; through considerations of binding constants and the kinetics of molecular interactions. The book ends with a thorough consideration of data analysis.

Table of Contents

Performing Quantitative Experiments with Biomolecules
1(18)
Affinity Constants
19(30)
Cooperativity in Binding
49(20)
Rate Constants for Binding and Dissociation
69(30)
Kinetics of Regulation and Cooperativity in Binding Reactions
99(18)
Rate Constants for a Two-step Binding Reaction
117(18)
Data Analysis
135(20)
Appendix 1: Equation Derivations 155(14)
Appendix 2: Resources and References 169(10)
Index 179

Supplemental Materials

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