Biochemistry of Signal Transduction and Regulation

by Krauss, Gerhard

• ISBN13: 9783527303786
• ISBN10: 3527303782
• Format: Paperback
• Copyright: 2001-12-01
• Publisher: WILEY JOHN & SONS INC

Summary

"This all-new edition of a best-selling text has been thoroughly updated to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity, the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis is made transparent for everyone with a basic knowledge in biochemistry or molecular biology. The unique textbook may be used as a companion for a course on regulation and signal transduction as well as an introductory reference to the field for students and researchers."--BOOK JACKET.

Table of Contents

The Regulation of Gene Expression	1	(88)
The Regulation of Enzyme Activity	89	(30)
Function and Structure of Signaling Pathways	119	(29)
Signaling by Nuclear Receptors	148	(25)
G-protein Coupled Signal Transmission Pathways	173	(43)
Intracellular Messenger Substances: ``Second Messengers''	216	(31)
Ser/Thr-specific Protein Kinases and Protein Phosphatases	247	(39)
Signal Transmission via Transmembrane Receptors with Tyrosine-specific Protein Kinase Activity	286	(38)
Signal Transmission via Ras Proteins	324	(26)
Intracellular Signal Transduction: the Protein Cascades of the MAP Kinase Pathways	350	(8)
Membrane Receptors with Associated Tyrosine Kinase Activity	358	(19)
Other Receptor Classes	377	(8)
Regulation of the Cell Cycle	385	(35)
Malfunction of Signaling Pathways and Tumorigenesis: Oncogenes and Tumor Suppressor Genes	420	(35)
Apoptosis	455	(18)
Ion Channels and Signal Transduction	473	(22)
Subject Index	495