Biochemistry of Signal Transduction and Regulation

by Krauss, Gerhard

• ISBN13: 9783527313976
• ISBN10: 3527313974
• Edition: 4th
• Format: Paperback
• Copyright: 2008-03-17
• Publisher: Vch Verlagsgesellschaft Mbh

Summary

This all-new edition of a best-selling text has been thoroughly updated to keep pace with the rapid progress in signal transduction research.With didactic skill and clarity, the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis is made transparent for everyone with a basic knowledge in biochemistry or molecular biology."Valuable up-to-date information on biochemistry of signal transduction and regulation" (AFS)"The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry)"This book is actually two books: Regulation and Signal Transduction." (Drug Research)

Author Biography

Gerhard Krauss is Professor of Biochemistry at the University of Bayreuth (Germany). His resarch is centered on the mechanism of interaction of DNA binding proteins and their target DNA. He is specifically interested in transcription factor, DNA methyl transferases and nucleotide excision repair.
The idea for a textbook on Signal Transduction and Gene Regulation originated from a lecture course that he has been teaching at Bayreuth since the middle of the 1990s.

Table of Contents

Regulation of Gene Expression

Regulation of Enzyme Activity

Function and Structure of Signaling Pathways

Signal Transduction by Nuclear Receptors

G-Protein-Coupled Signal Transmission Pathways

Intracellular Messenger Substances: "Second Messengers"

Ser/Thr-Specific Protein Kinases and Protein Phosphatases

Signal Transmission via Transmembrane

Receptors with Tyrosine-Specific Protein Kinase Activity

Signal Transmission via Ras Proteins

Intracellular Signal Transduction: Protein Kinase Cascades of MAP Kinase Pathways

Membrane Receptors with Associated Tyrosine Kinase Activity

Transmembrane Receptors with Intrinsic Ser/Thr-Kinase

Activity and Signal Transduction in the "Two-Component Pathway"

Regulation of the Cell Cycle

Malfunction of Signaling Pathways and Tumorigenesis: Oncogenes and Tumor Suppressor Genes

Apoptosis

Table of Contents provided by Publisher. All Rights Reserved.