Bioinformatics and Functional Genomics

by Pevsner, Jonathan

• ISBN13: 9780471682288
• ISBN10: 0471682284
• eBook ISBN(s): 9780471459170
• Edition: 1st
• Format: Hardcover
• Copyright: 2004-11-01
• Publisher: WILEY JOHN & SONS INC
• More Book Details

Summary

Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.

Author Biography

Jonathan Pevsner: Department of Neurology, Kennedy Krieger Institute and Department of Neuroscience and Division of Health Sciences Informatics, The Johns Hopkins School of Medicine, Baltimore, Maryland

Table of Contents

Analyzing DNA, RNA, and Protein Sequences in Databases
Introduction	p. 3
Access to Sequence Data and Literature Information	p. 15
Pairwise Sequence Alignment	p. 41
Basic Local Alignment Search Tool (BLAST)	p. 87
Advanced BLAST Searching	p. 127
Genomewide Analysis of RNA and Protein
Bioinformatic Approaches to Gene Expression	p. 157
Gene Expression: Microarray Data Analysis	p. 189
Protein Analysis and Proteomics	p. 223
Protein Structure	p. 273
Multiple Sequence Alignment	p. 319
Molecular Phylogeny and Evolution	p. 357
Genome Analysis
Completed Genomes and the Tree of Life	p. 397
Completed Genomes: Viruses	p. 437
Completed Genomes: Bacteria and Archaea	p. 465
Eukaryotic Genomes: Fungi	p. 503
Eukaryotic Genomes: From Parasites to Primates	p. 539
Human Genome	p. 607
Human Disease	p. 647
Table of Contents provided by Rittenhouse. All Rights Reserved.