Bioinformatics for Immunomics

by Flower, Darren R.; Davies, Matthew N.; Ranganathan, Shoba

• ISBN13: 9781441905390
• ISBN10: 1441905391
• Format: Hardcover
• Copyright: 2009-09-01
• Publisher: Springer Verlag

Summary

This peer-reviewed book series offers insight on immunology for the 21st century. The technological revolution has borne advances in high-throughput instrumentation and information technology, initiating a renaissance for biomathematics, and biostatistics. Cross-fertilization between genomics and immunology has led to a new field called immunomics, transforming the way in which theoretical, clinical and applied immunology are practiced. Immunomics Reviews will cover integrative approaches and applications to the theory and practice of immunology and explore synergistic effects resulting from a combination of technological advances and the latest analytical tools with the traditional fields of basic and clinical immunology.

Table of Contents

Computational Vaccinology	p. 1
The Immuno Polymorphism Database	p. 21
The IMGT/HLA Database	p. 33
Ontology Development for the Immune Epitope Database	p. 47
Tepidas: A DAS Server for Integrating T-Cell Epitope Annotations	p. 57
Databases and Web-Based Tools for Innate Immunity	p. 67
Structural Immunoinformatics: Understanding MHC-Peptide-TR Binding	p. 77
Discovery of Conserved Epitopes Through Sequence Variability Analyses	p. 95
Tunable Detectors for Artificial Immune Systems: From Model to Algorithm	p. 103
Defining the Elusive Molecular Self	p. 129
A Bioinformatic Platform for a Bayesian, Multiphased, Multilevel Analysis in Immunogenomics	p. 157
Index	p. 187
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