Biological Safety

by Fleming, Diane O., Ph.D.; Hunt, Debra Long

• ISBN13: 9781555811808
• ISBN10: 1555811809
• Format: Hardcover
• Copyright: 2000-12-01
• Publisher: Amer Society for Microbiology

Summary

Written by recognized authorities with decades of experience in the biological safety field, the third edition of this best-selling volume is an essential resource as well as an excellent text for courses in biosafety. The epidemiology of laboratory-associated infections, including some previously unreported cases, is thoroughly covered. Detailed chapters cover hazard assessments of the wide range of pathogens and biological toxins encountered in biomedical laboratories as well as other occupational settings. All facets of hazard control, from personal protective equipment to institution-wide provisions and policies, are discussed.

Table of Contents

Contributors	ix
Foreword	xv
Robert W. McKinney
I Hazard Identification
Indigenous and Pathogenic Microorganisms of Humans	3	(8)
Susan E. Sharp
Pathogens of Mice, Rats, and Rabbits	11	(16)
David G. Baker
Laboratory, Growth Chamber, and Greenhouse Microbial Safety: Plant Pathogens and Plant-Associated Microorganisms of Significance to Human Health	27	(8)
Anne K. Vidaver
Sue Tolin
Epidemiology of Laboratory-Associated Infections	35	(22)
A. Lynn Harding
Karen Brandt Byers
II Hazard Assessment
Risk Assessment of Biological Hazards	57	(8)
Diane O. Fleming
Bacterial Pathogens	65	(24)
Joseph H. Coggin, Jr.
Protozoa and Helminths	89	(22)
Barbara L. Herwaldt
Mycotic Agents of Human Disease	111	(10)
David W. Warnock
Zoonoses	121	(30)
Christian E. Newcomer
Transmission and Control of Laboratory-Acquired Hepatitis Infection	151	(12)
Martin S. Favero
Walter W. Bond
Human Immunodeficiency Virus Type 1 and Other Blood-Borne Pathogens	163	(24)
Debra L. Hunt
Biosafety of Prion Diseases	187	(22)
Henry Baron
Stanley B. Prusiner
Biosafety Precautions for Mycobacterium tuberculosis and Other Airborne Pathogens	209	(12)
Mary J. R. Gilchrist
Diane O. Fleming
Cell Lines: Applications and Biosafety	221	(20)
Otto Doblhoff-Dier
Glyn Stacey
Allergies Associated with the Use of Latex	241	(8)
Marilyn V. Howarth
Allergens of Animal and Biological Systems	249	(12)
Wanda Phipatanakul
Robert A. Wood
Biological Toxins	261	(12)
Randall S. Morin
Joseph P. Kozlovac
Pfiesteria	273	(10)
Janet S. Peterson
III Hazard Control
Design of Biomedical Laboratory Facilities	283	(30)
Jonathan T. Crane
Jonathan Y. Richmond
Primary Barriers: Biological Safety Cabinets, Fume Hoods, and Glove Boxes	313	(18)
David G. Stuart
Other Primary Barriers and Equipment-Associated Hazards	331	(8)
Elizabeth A. Gilman
Richard C. Fink
Personal Respiratory Protection	339	(16)
Nicole Vars McCullough
Standard (Universal) Precautions for Human Specimens	355	(14)
Debra L. Hunt
Prudent Biosafety Practices	369	(14)
Diane O. Fleming
Decontamination, Sterilization, Disinfection, and Antisepsis	383	(20)
Donald Vesley
James L. Lauer
Robert J. Hawley
Regulated Medical Waste Handling and Disposal	403	(8)
John H. Keene
Packaging and Shipping Biological Materials	411	(18)
James McKay
Diane O. Fleming
IV Administrative Controls
Leadership and Management in Biological Safety	429	(14)
Joseph Van Houten
Elements of a Biosafety Program	443	(20)
Richard W. Gilpin
Biosafety Compliance: a Global Perspective	463	(18)
Richard Rebar
Halley Moriyama
Biological Safety Program Evaluation	481	(16)
Robert J. Hashimoto
Lawrence M. Gibbs
Occupational Health and Medical Surveillance	497	(20)
Joseph H. Coggin, Jr.
Robert Schwartz
V Special Considerations for Biosafety
Biosafety in the Teaching Laboratory	517	(16)
David M. Carlberg
Michael R. Yeaman
Biosafety in the Pharmaceutical Industry	533	(8)
Paul J. Meechan
Joseph Gyuris
Randolph Greasham
Wayne Herber
Biosafety Considerations for Large-Scale Production of Microorganisms	541	(16)
Mary L. Cipriano
Biosafety in the Virology Laboratory: Risk Assessment Considerations	557	(10)
Michael P. Kiley
Bioterrorism and Biological Safety	567	(12)
Robert J. Hawley
Edward M. Eitzen, Jr.
Biosafety and Viral Gene Transfer Vectors	579	(20)
Thomas A. Kost
J. Patrick Condreay
Claudia A. Mickelson
Biosafety and the Internet	599	(166)
Stefan Wagener
Appendixes
1 Biosafety in Microbiological and Biomedical Laboratories	609	(92)
U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, and National Institutes of Health
2 Occupational Exposure to Bloodborne Pathogens; Final Rule (29 CFR Part 1910.1030)	701	(12)
U.S. Department of Labor, Occupational Safety and Health Administration
3 NIH Guidelines for Research Involving Recombinant DNA Molecules	713	(52)
National Institutes of Health
Index	765