Biomarkers of Disease: An Evidence-Based Approach

by Edited by Andrew K. Trull , Lawrence M. Demers , David W. Holt , Atholl Johnston , J. Michael Tredger , Christopher P. Price

• ISBN13: 9780521088602
• ISBN10: 0521088607
• Edition: 1st
• Format: Paperback
• Copyright: 2008-10-30
• Publisher: Cambridge University Press

Summary

This publication takes a critical, evidence-based look at the efficacy of diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of products being brought out by the pharmaceutical industry. Some of these assist in diagnosis, others provide a means of monitoring the state of progression of disease and the effectiveness of therapeutic options. However, in many cases the evidence which supports the use of these methods as opposed to traditional biochemical tests has not yet been demonstrated, and it is intended that this volume will help clarify the strengths and weaknesses of using these biomarkers across a wide range of applications and in the various organs of the body. This approach will provide pathologists, clinical biochemists and medical laboratory scientists with an invaluable overview of the diverse applications of biomarkers in medicine.

Table of Contents

Assessing and Utilising the Diagnostic and Prognostic Power of Biomarkers

Biomarkers of Kidney Disease and Dysfunction

Biomarkers of Bone Disease and Dysfunction

Biomarkers of Liver Disease and Dysfunction

Biomarkers of Gastrointestinal Disease and Dysfunction

Biomarkers in Toxicology

Biomarkers of Cardiovascular Disease and Dysfunction

Biomarkers of Neurological Disease and Dysfunction

Biomarkers in Transplantation

Table of Contents provided by Publisher. All Rights Reserved.