Biomems and Biomedical Nanotechnology

by Lee, Abraham P.; Lee, James; Ferrari, Mauro

• ISBN13: 9780387255637
• ISBN10: 038725563X
• Edition: 1st
• Format: Hardcover
• Copyright: 2006-10-15
• Publisher: Springer Verlag

Summary

Volume 1 of the multi-volume reference, BioMEMS and Biomedical Nanotechnology, focuses on synthetic nanodevices and the synthesis of nanomaterials and the generation of nanoscale features. The nanomaterials include polymeric microspheres and nanostructures, carbon nanotubes, silicon, silicon dioxide, and iron oxide. There is also a chapter on the characterization of critical nanostructures for bio applications such as nanochannels and nanopores. The second part involves hybrid synthetic-biomolecular nanodevices that utilize the self assembly properties of both biomolecules and synthetic materials. There is a chapter discussing the structure-function relations between biomolecular (protein) and inorganic interfaces. The third part gives the theoretical underpinning of bio nanodevices covering computation methods, informatics, and mechanics. These fundamentals are critical in designing the next generation nanodevices and also understanding the interaction between nanodevices and biological systems to enable more efficient in vitro and in vivo bio applications.An accompanying CD contains high resolution reproductions of all figures appearing in the volumes of this reference, many of which are in color.

Author Biography

Abe Lee has been working on micro/ and nanotechnology for biomedical and biotech applications since 1992. His recent research focuses on the development of integrated micro and nano fluidic chip processors for the following applications: point-of-care diagnostics, "smart" nanomedicine for early detection and treatment, stem cell biology and therapeutics, the synthesis of novel and pure materials, and biosensors to detect environmental and terrorism threats. He has over 30 peer reviewed publications and over 30 issued US patents. I am also subject editor for the Journal of Microelectromechanical Systems and member of the International Advisory Editorial Board for the Lab on a Chip journal.Jim Lee's research interest includes BioMEMS/NEMS, and polymer micro/nanotechnology. In the last 4 years, he has over 20 refereed journal publications, 2 book chapters, and 5 patents in these areas. He is now leading an NSF Nanoscale Science and Engineering Center for Affordable Nanoengineering of Polymer Biomedical Devices at OSU.Professor Mauro Ferrari is a pioneer in the fields of bioMEMS and biomedical nanotechnology. As a leading academic, a dedicated entrepreneur, and a vision setter for the Nation's premier Federal programs in nanomedicine, he brings a three-fold vantage perspective to his roles as Editor-in-Chief for this work. Dr. Ferrari has authored or co-authored over 150 scientific publications, 6 books, and over 20 US and International patents. Dr. Ferrari is also Editor-in-Chief of Biomedical Microdevices and series editor of the new Springer series on Emerging Biomedical Technologies.Several private sector companies originated from his laboratories at the Ohio State University and the University of California at Berkeley over the years. On a Federal assignment as Special Expert in Nanotechnology and Eminent Scholar, he has provided the scientific leadership for the development of the Alliance for Cancer Nanotechnology of the National Cancer Institute, the world-largest medical nanotechnology operation to date. Dr. Ferrari trained in mathematical physics in Italy, obtained his Master's and Ph.D. in Mechanical Engineering at Berkeley, attended medical school at The Ohio State University, and served in faculty positions in Materials Science and Engineering, and Civil and Environmental Engineering in Berkeley, where he was first tenured. At Ohio State he currently serves as Professor of Internal Medicine, Division of Hematology and Oncology, as Edgar Hendrickson Professor of Biomedical Engineering, and as Professor of Mechanical Engineering. He is Associate Director of the Dorothy M. Davis Heart and Lung Research Institute, and the University's Associate Vice President for Health Science, Technology and Commercialization. 

Table of Contents

Synthetic Nanodevices for Biotechnology and Biomedicine: Biomolecular Sensing for Cancer Diagnostics Using Carbon Nanotubes

Microspheres for Drug Delivery

X Nanoscale Polymer Fabrication for Biomedical Applications

- 3D Micro- and Nanofabrication and their Medical Applications

Sacrificial Oxide Layer for Drug Delivery

Carbon Nanotube Biosensors

Characterization Methods for Quality Control of Nanopore and Nanochannel Membranes

Magnetic Nanopaarticles for MR Imaging

Hybrid Synthetic and Biomolecular Nanodevices: Polymer Design for Nonviral Gene Delivery

Dip-pen Technologies for Biomolecular Devices

Engineered Inorganic-Binding Polypeptides for Bionanotechnology

Nanodevices in Biomedical Applications

Computation, Simulation, and Informatics for Bionano Devices: Modeling Biomolecular Transport at the Nanoscale

Nanotechnology in Cancer Drug Therapy: A Biocomputational Approach

Nanomechanics and Tissue Pathology

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