Bipolar Disorder : Clinical and Neurobiological Foundations

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  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2010-10-11
  • Publisher: Wiley
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Bipolar disorder is the most complex psychiatric disorder with different types of mood episodes, subtypes, varied course, and significant co-morbidity. Not surprisingly, this complexity poses unique challenges to clinicians for optimal management of those with bipolar disorder. There has been an explosion of research into the causes and treatment of this condition over the past two decades. It is a daunting task for a practising clinician to make sense of this research and to remain up to date with progress in the understanding of the neurobiology and treatment of bipolar disorder. This book synthesizes and translates the vast array of research knowledge into information that is clinically relevant and meaningful for a clinician. The book provides a comprehensive, yet focused, reference work on bipolar disorder for both trainees and practising psychiatrists. The two editors are leaders in the field who have published extensively on bipolar disorder. They have assembled a team of experts from around the world: in many instances, chapters are co-authored by people from different continents, bringing a truly international perspective to this important topic. The book covers the basic science of the pathology underlying bipolar disorder but addresses the clinical aspects of the disease throughout. The book comprises four sections: Descriptive Aspectsissues ranging from how the concept of bipolar disorder has evolved over the years to new information about neurocognitive impairment, creativity and economic productivity, and to discussion of the deliberations of the DSM-V committee on changes in diagnostic categories and criteria. Biologythe contribution of genes to this disorder, changes in circadian rhythms, what we know about brain changes and the role of oxidative stress. Biological Treatment and Psychosocial Treatment all the latest information about pharmacological and psychological treatments and the optimal management of this condition. If you want to provide state-of-the-art care to your bipolar patients, be sure to consult this authoritative reference.

Author Biography

Dr. Yatham leads a Canadian consortium on bipolar disorder, testing new treatments for bipolar disorder using pragmatic and controlled trials with substantial funding from the Canadian Institutes of Health Research. He co-led the development of the Canadian guidelines for treatment of bipolar disorder in 1997; revised the guidelines for 2005 which were published with International Commentaries in Bipolar Disorders Journal. Dr Yatham is Chair of the bipolar group of the Canadian Network for Mood and Anxiety Treatments ; actively involved at a national and international level in continuing medical education and public education on diagnosis and treatment of bipolar disorder for psychiatrists, family physicians, and the general public. Currently the President for the International Society for Bipolar Disorders and on the editorial boards of a number of journals including Bipolar Disorders, Brain Pharmacology, Human Psychopharmacology, Quarterly Journal of Mental Health. He has published over 140 papers in peer-reviewed international journals and presented his research work at numerous international conferences. He was a recipient of the Michael Smith Foundation Senior Scholar Award (2001).

Professor Maj is President of the World Psychiatric Association; President of the Italian Psychiatric Association (since 2000); President of the Italian Society of Biological Psychiatry (since 1990); Association of European Psychiatrists Secretary-General (2001-2002) and President (2003-4); Editor of World Psychiatry and member of the Editorial Board of several scientific journals.

Table of Contents

From Mania to Bipolar Disorder
Clinical Features and Subtypes of Bipolar Disorder
The Long term Course and Outcome of Bipolar I and Bipolar II Disorder
Comorbidity in Bipolar Disorder: A Focus on Addiction and Anxiety Disorders
DSM-V Perspectives on Classification of Bipolar Disorder
Update on the Epidemiology of Bipolar Disorder
Suicide and Bipolar Disorder
Neurocognition in Bipolar Disorder
The Genius-Insanity Debate: Focus on Bipolarity, Temperament, Creativity and Leadership
Economics of Bipolar Disorder
An introduction to the neurobiology of bipolar illness onset, recurrence and progression
Genetics of Bipolar Disorder
Structural Brain Imaging in Bipolar Disorder
Functional Magnetic Resonance Imaging, Diffusion Tensor Imaging, and Magnetic Resonance Spectroscopy in Bipolar Disorder
Functional Brain Imaging Studies in Bipolar Disorder: Focus on Cerebral Metabolism and Blood Flow
Neurotransmitter Systems in Bipolar Disorder
Molecular Biology of Bipolar Disorder
Mitochondrial Dysfunction and Oxidative Stress
Neuroendocrinology of Bipolar Illness
Circadian Rhythms and Sleep in Bipolar Disorder
Treatment Adherence in Bipolar Disorder
Acute Mania
Pharmacological Treatment of Bipolar Depression
Maintenance Treatment
Rapid Cycling Bipolar Disorder: Phenomenology and Treatment
Management of Bipolar II Disorder
Management of Comorbidity in Bipolar Disorder
Bipolar disorder and safety monitoring for clinicians in 2009: A review of the evidence and the implications
Somatic Treatments for Bipolar Disorder
Novel Therapeutic Strategies for Bipolar Disorder
Psychoeducation as a core element of psychological approaches for Bipolar Disorder
Cognitive-Behavioural Therapy for Bipolar Disorder
Interpersonal and Social RhythmTherapy for Bipolar Disorder
Family therapy approaches to Bipolar Disorder
Collaborative Care for Bipolar Disorder
Bipolar Disorder in Women
Phenomenology and Treatment of Bipolar I Disorder in Children: A Critical Review
Bipolar Disorder in the Elderly
Table of Contents provided by Publisher. All Rights Reserved.

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