Blood Banking and Transfusion Medicine

by Hillyer, Christopher D.

• ISBN13: 9780443069819
• ISBN10: 0443069816
• Edition: 2nd
• Format: Hardcover
• Copyright: 2006-10-01
• Publisher: CHURCHILL LIVINGSTONE

Summary

Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with todays most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, youll find coverage here thats second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether youre new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.

Table of Contents

A brief history of blood transfusion	p. 3
Principles of the immune system central to transfusion medicine	p. 15
Principles of the complement system central to transfusion medicine	p. 30
Principles of red blood cell allo- and autoantibody formation and function	p. 43
Membrane blood group antigens and antibodies	p. 53
ABO and related antigens and antibodies	p. 69
Rh, kell, duffy, and kidd antigens and antibodies	p. 80
Other blood group antigens and antibodies	p. 96
Human platelet antigens	p. 112
Human leukocyte and granulocyte antigens and antibodies : the HLA and HNA systems	p. 129
Blood donation and collection	p. 157
Blood manufacturing : component preparation, storage, and transportation	p. 183
Red blood cell metabolism during storage : basic principles and practical aspects	p. 205
Infectious disease testing : basic principles and practical aspects	p. 212
Regulatory principles and issues central to blood banking and transfusion medicine	p. 223
Quality assurance, control and improvement, and accreditation	p. 230
Legal principles and issues central to transfusion medicine	p. 238
Packed red blood cells and related products	p. 250
Fresh frozen plasma and related products	p. 259
Cryoprecipitate and related products	p. 270
Albumin	p. 278
IVIG and derivatives	p. 288
Platelets and related products	p. 308
Granulocytes	p. 342
Coagulation factor preparations	p. 352
Leukocyte-reduced products	p. 359
Virus-safe products : pathogen reduction and inactivation	p. 383
Irradiated products	p. 397
Washed and volume-reduced blood components	p. 410
Blood management : conservation, salvage, and alternatives to allogeneic transfusion	p. 419
Blood substitutes : basic principles and practical aspects	p. 435
Red cell transfusion in perioperative and critically ill patients	p. 445
Post-transfusion red blood cell and platelet survival and kinetics : basic principles and practical aspects	p. 455
Transfusion of the patient with congenital coagulation defects	p. 467
Transfusion of the patient with acquired coagulation defects	p. 482
Obstetric and intrauterine transfusion	p. 496
Transfusion of neonates and pediatric patients	p. 510
Transfusion of the hemoglobinopathy patient	p. 523
Transfusion to bone marrow or solid organ transplant recipients	p. 539
Transfusion of the platelet-refractory patient	p. 551
Autoimmune hemolytic anemias	p. 557
Transfusion in economically restricted countries and developing countries	p. 571
Hepatitis A, B, and non-A, non-B, non-C viruses	p. 584
Hepatitis C	p. 592
HIV, HTLV, and other retroviruses	p. 600
Human herpesvirus infections	p. 618
Bacterial infections : bacterial contamination, testing, and post-transfusion complications	p. 639
Other viral, bacterial, parasitic, and prion-based infectious complications	p. 652
Hemolytic transfusion reactions : acute and delayed	p. 668
Febrile, allergic, and other noninfectious transfusion reactions	p. 677
Transfusion-related acute lung injury	p. 691
Transfusion-related immunomodulation	p. 701
Post-transfusion engraftment syndromes : microchimerism and TA-GVHD	p. 713
Therapeutic apheresis : basic principles and practical aspects	p. 727
Therapeutic plasma exchange	p. 738
Therapeutic cytapheresis	p. 765
The role of transfusion medicine in cellular therapies	p. 780
Bone marrow and peripheral blood stem cell transplantation	p. 787
Umbilical cord blood stem cells : collection, processing, and transplantation	p. 823
Collection and processing of peripheral blood stem cells and bone marrow	p. 833
Tissue banking in the hospital setting	p. 853
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