Blood Flow in Artificial Organs and Cardiovascular Prostheses

by Barbenel, J. C.; Fisher, A. C.; Gaylor, J. D. S.; Angerson, W. J.; Sheldon, C. D.

• ISBN13: 9780198576471
• ISBN10: 0198576471
• Format: Hardcover
• Copyright: 1989-02-16
• Publisher: Oxford University Press

Summary

This volume brings together the work of many researchers interested in blood flow in artificial organs and cardiovascular prostheses. Such devices have had a dramatic impact on medicine. The use of blood oxygenators and dialysers has made surgical procedures like major open-heart surgery possible. Implantable replacement heart valves and blood vessels are other important examples of devices which have extended the clinician's choice of treatment, and prolonged and improved the quality of patients' lives. The development of these artificial organs and cardiovascular prostheses has been based on interdisciplinary research involving clinicians, engineers, and scientists from a range of fields. The further improvement and development of these devices remain an important aim of such collaborative research as that represented in this work.

Table of Contents

Influence of Haemodynamic Factors in Improving Vascular Prosthetic Design

Clinical and Laboratory Assessment of Prosthetic Heart Valves

Leaflet Design and Manufacture in Pericardial Heart Valves

The Anisotropy of Bovine Pericardium

In Vitro Study of the Function of Four Size 19-mm Prosthetic Heart Valves in the Arotic Position

The Hydrodynamic Performance of Heart Valve Substitutes

Investigation into Leakage Design in Prosthetic Heart Valves

Changes in Pericardial Heterograft Leaflets In Vitro

An Isotope Imaging Technique for Limb Blood Flow Measurement and its Role in the Assessment of Aerterial Bypass Grafts

Secondary Intraventricular Flow Patterns and Fluid Mechanics of the Mitral Valve

Thrombosis and Artificial Surfaces

Blood-Membrane Interactions

Biomaterials and the Immune Response

Induced Platelet Aggregation in Blood Exposed to Biomaterials

The Evaluation of Biomaterials and Antithrombotic Agents in a Rat Extracorporeal Model

Modification of Dacron Graft Thrombogenicity and Porosity by Preclotting

First-Pass Haemolysis in Collagen and Gelatin Impregnated Dacron Grafts

Influence of Gore-Text Aoto-Bifermoral Grafts on Platelet and Fibrinogen Kinetics

Biocompatibility Studies on New Cellulose Based and Synthetic Haemodialysis Membranes

The Influence of Vortex Mixing on the Performance of Artificial Organs

Modelling of Gas Exchange Oxygenators

The Effect of a Cell-Free Layer on the Rate of Oxygen Transfer in a Membrane Oxygenator

Blood Viscosity and Cell Deformability

The Temporal Variation in Platelet Count and Volume After Open-Heart Surgery with Cardiopulmonary Bypass

Whole Blood Viscosity Measurement Using a Capillary Tube Viscometer

An Adaptive System for the Determination of Red Cell Volume Distributions by Coulter Counting

The Variation of Erythrocyte Sedimentation Rate with Red Cell Concentration

A Re-Assessment of Whole Blood Viscosity in Raynaud's Phenomenon

Some Difficulties in the Measurement of Whole-Blood Viscosities by Means of Certain Rotational Instruments

Steady Non-Newtonian Flow Through Tapered Tubes

Flow Distribution in Membrane Oxygenators

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