The BMT Data Book

Summary

The BMT Data Book is an essential guide to the data, outcome studies and complex decision-making processes involved in blood and marrow stem cell transplantation. Organized according to types of diseases and procedures, it contains more than hundred tables, figures and algorithms that reflect up-to-date research and give guidance on the choices between stem cell versus bone marrow transplantation, autologous versus allogeneic transplantation, and conventional versus experimental treatments. This new edition summarizes research of the last 5 years and gives mature data for all established indications, such as acute myeloid leukemia, myelodysplastic syndromes, Hodgkin's and Non-Hodgkin's lymphomas. In addition, controversies and new indications - like renal cell cancer and autoimmune disorders - are discussed plus new drugs and therapies, new stem cell sources (cord blood), new transplant protocols (reduced-intensity conditioning), and a guide to electronic databases.

Author Biography

Reinhold Munker is Associate Professor of Medicine, Department of Medicine, Division of Hematology/Oncology, Louisiana State University Health Sciences Center, USA. Hillard M. Lazarus is Professor of Medicine, Case Western Reserve University, and Director, Blood and Marrow Transplant Program, University Hospitals Case Medical Center, USA. Kerry Atkinson is Professor of Medicine, University of Queensland; Director of Allogeneic Stem Cell Therapies; Director, Mater Health Services Cell Therapy Quality Management System; and Head, Biotherapy Program, Mater Medical Research Institute, Mater Adult Hospital, Australia.

List of contributors	p. ix
Foreword	p. xi
Preface	p. xiii
Acknowledgments	p. xvi
Basic science	p. 1
Basic science	p. 3
Hematologic malignancies	p. 21
Therapeutic decision making in BMT/SCT for acute myeloid leukemia	p. 23
Therapeutic decision making in BMT/SCT for acute lymphoblastic leukemia	p. 41
Therapeutic decision making in BMT/SCT for chronic myeloid leukemia and other myeloproliferative syndromes	p. 57
Therapeutic decision making in BMT/SCT for chronic lymphatic leukemia	p. 71
Therapeutic decision making in BMT/SCT for myelodysplasia	p. 85
Therapeutic decision making in BMT/SCT for non-Hodgkin Lymphoma	p. 99
Therapeutic decision making in BMT/SCT for Hodgkin lymphoma	p. 127
Therapeutic decision making in hematopoietic stem cell transplantation for multiple myeloma	p. 139
Therapeutic decision making in BMT/SCT for amyloidosis	p. 157
Solid tumors	p. 163
Therapeutic decision making in stem cell transplantation for breast cancer	p. 165
Therapeutic decision making in BMT/SCT for nonseminomatous germ cell tumor of testis (NSGCT)	p. 169
Therapeutic decision making in BMT/SCT for renal cell cancer	p. 177
Therapeutic decision making in BMT/SCT for soft tissue sarcomas	p. 189
Nonmalignant disorders	p. 195
Therapeutic decision making in BMT/SCT for severe aplastic anemia	p. 197
Therapeutic decision making in BMT/SCT for congenital immunodeficiencies	p. 205
Therapeutic decision making in BMT/SCT for hemoglobinopathies	p. 215
Therapeutic decision making in BMT/SCT for autoimmune disorders	p. 227
Practical aspects and procedures	p. 233
Practical aspects and procedures, including conditioning protocols and haploidentical transplantation	p. 235
Umbilical cord blood as alternative allogeneic graft source: clinical banking and transplant outcomes	p. 301
Complications	p. 311
Pathobiology of graft-versus-host disease	p. 313
Diagnosis and treatment of graft-versus-host-disease	p. 331
Management and prophylaxis of infections after BMT/SCT	p. 357
Organ-related and miscellaneous complications	p. 379
The BMT/SCT pharmacopoeia	p. 429
The BMT/SCT pharmacopoeia	p. 431
HLA-testing and laboratory medicine	p. 493
HLA-testing and laboratory medicine	p. 495
Appendix	p. 511
Index	p. 515
Table of Contents provided by Ingram. All Rights Reserved.

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