Brain Somatic Cross-Talk and the Central Control of Metabolism

by Kordon, Claude; Robinson, I.; Hanoune, J.; Dantzer, R.; Christen, Y.; Kordon, Claude

• ISBN13: 9783540000907
• ISBN10: 3540000909
• Format: Hardcover
• Copyright: 2003-03-01
• Publisher: Springer Verlag

Summary

The present book summarizes presentations to an IPSEN Foundation Conference on Brain Somatic Cross Talk and the Central Control of Metabolism, organised in 2002. It proposes a state-of-the-art outline of the multifaceted neuronal networks which serve the highly selective purpose of adapting growth, metabolism, reproduction, and more generally energy consumption to the availability of food resources. The physiology of over twenty neurotransmitters and peptides underlying these functions is presented, together with their neuronal targets, their mechanism of action and their current or anticipated relevance for pathology. Functions covered are as diverse as regulation of food intake and sleep, adaptation to emergency situations, and finally mental disorders - as well as early, irreversible imprinting of epigenetic influences on physiological and behavioural patterns, which in some cases can even be transmitted from generation to generation. Book jacket.

Table of Contents

Interactions of Growth Hormone Secretagogues with Leptin-Sensitive Brain Networks	1	(14)
S. L. Dickson
L. Y. C. Tung
S. Lall
J.-O. Jansson
A. K. Hewson
Leptin and the Neural Circuit Regulating body Weight and Metabolism	15	(22)
M. J. Friedman
Role of the Growth Hormone Secretagogue Receptor in the Central Nervous System	37	(16)
R. G. Smith
L. Betancourt
Y. Sun
Regulation of Galanin-Like Peptide (GALP) in the Brain and Posterior Pituitary: A Review	53	(12)
A. Jureus
D. K. Clifton
R. A. Steiner
Ghrelin and the Growth Hormone Neuroendocrine Axis	65	(16)
G. S. Tannenbaum
J. Epelbaum
C. Y. Bowers
Adipose Tissues as Part of the Immune System: Role of Leptin and Cytokines	81	(10)
L. Penicaud
B. Cousin
P. Laharrague
C. Leloup
A. Lorsignol
L. Casteilla
Regulation of Body Weight Homeostasis During Pregnancy and Lactation	91	(8)
M. C. Garcia
R. M. Senaris
J. E. Caminos
M. Lopez
R. Nogueiras
O. Gualillo
F. Casanueva
C. Dieguez
Ghrelin: From GH Control to Feeding Behaviour and Sleep Regulatio	99	(12)
M.-T. Bluet-Pajot
V. Tolle
M.-H. Bassant
C. Kordon
P. Zizzari
F. Poindessous-Jazat
C. Tomasetto
M. C. Rio
B. Estour
C. Foulon
R. Dardennes
J. Epelbaum
Effect of Leptin on Fatless Mice	111	(10)
I. Shimomura
Leptin, Growth and Reproduction	121	(22)
M. L. Aubert
B. Sudre
P. D. Raposinho
D. Vauthay
D. D. Pierroz
F. P. Pralong
An Emerging Role of Leptin in Clinical Psychiatry	143	(12)
T. Pollmacher
Genomic approach to common human obesity	155	(10)
P. Boutini
P. Froguel
The Epigenetic Inheritance Hypothesis	165	(26)
C. Junien
Subject Index	191