Preface | p. xi |
Acknowledgments | p. xiii |
General Properties of Microorganisms | p. 1 |
The microbial world | p. 1 |
Bacterial structure | p. 3 |
Bacterial growth | p. 9 |
Bacterial cultivation | p. 11 |
Bacterial metabolism | p. 13 |
Cell wall synthesis | p. 15 |
Sterilization and disinfection | p. 15 |
Antimicrobial chemotherapy | p. 16 |
Toxins | p. 21 |
Bacteriophages | p. 22 |
Review test | p. 25 |
Bacterial Genetics | p. 29 |
Organization of genetic information--general concepts | p. 29 |
Comparison of prokaryotic and eukaryotic genomes | p. 29 |
Gene transfer between organisms | p. 31 |
Gene expression | p. 34 |
Mutation | p. 35 |
Review test | p. 37 |
Bacteriology | p. 39 |
Upper Respiratory Tract Infections | p. 39 |
Streptococcus pyogenes (Group A) | p. 39 |
Haemophilus influenzae | p. 43 |
Corynebacterium diphtheriae | p. 44 |
Fusobacterium nucleatum | p. 46 |
Lower Respiratory Tract Infections | p. 46 |
Streptococcus pneumoniae | p. 46 |
Mycoplasma pneumoniae | p. 48 |
Legionella pneumophila | p. 49 |
Bordetella pertussis | p. 50 |
Chlamydia psittaci | p. 52 |
Chlamydia pneumoniae | p. 53 |
Mycobacterium tuberculosis | p. 53 |
Mycobacterium avium-intracellulare (MAI or MAC for M. avium complex) | p. 56 |
Nocardia | p. 57 |
Prevotella melaninogenica | p. 57 |
Other | p. 58 |
Gastrointestinal Tract Infections | p. 58 |
Enterobacteriaceae Family (Enterics) | p. 58 |
Salmonella | p. 62 |
Shigella | p. 64 |
Escherichia coli | p. 65 |
Vibrio cholerae | p. 66 |
Staphylococcus aureus | p. 68 |
Campylobacter jejuni | p. 68 |
Helicobacter pylori | p. 69 |
Clostridium botulinum | p. 70 |
Clostridium difficile | p. 71 |
Bacteroides fragilis | p. 72 |
Genitourinary Tract Infections | p. 73 |
Escherichia coli | p. 73 |
Staphylococcus saprophyticus | p. 74 |
Proteus mirabilis | p. 74 |
Enterococcus faecalis | p. 74 |
Neisseria gonorrhoeae | p. 75 |
Treponema pallidum | p. 77 |
Chlamydia trachomatis | p. 79 |
Bacteroides fragilis | p. 80 |
Central Nervous System Infections | p. 80 |
Streptococcus agalactiae | p. 80 |
Neisseria meningitidis | p. 81 |
Clostridium tetani | p. 83 |
Other | p. 84 |
Cardiovascular Infections | p. 85 |
Viridans streptococci | p. 85 |
Enterococci | p. 86 |
Staphylococcus aureus | p. 86 |
Staphylococcus epidermidis | p. 86 |
Pseudomonas aeruginosa | p. 87 |
Skin and Soft Tissue Infections | p. 87 |
Staphylococcus aureus | p. 87 |
Clostridium perfringens | p. 89 |
Pseudomonas aeruginosa | p. 90 |
Streptococcus pyogenes | p. 91 |
Bacteroides fragilis | p. 92 |
Other organisms | p. 92 |
Eye and Ear Infections | p. 92 |
Chlamydia trachomatis | p. 92 |
Neisseria gonorrhoeae | p. 93 |
Haemophilus influenzae | p. 93 |
Streptococcus pneumoniae | p. 93 |
Haemophilus influenzae | p. 93 |
Pseudomonas aeruginosa | p. 93 |
Multisystem Infections | p. 93 |
Listeria monocytogenes | p. 93 |
Yersinia pestis | p. 95 |
Borrelia burgdorferi | p. 95 |
Ehrlichia | p. 97 |
Rickettsia rickettsii | p. 97 |
Coxiella burnetii | p. 99 |
Francisella tularensis | p. 100 |
Brucella | p. 100 |
Bacillus anthracis | p. 101 |
Actinomyces | p. 102 |
Staphylococcus aureus | p. 103 |
Staphylococcus aureus | p. 104 |
Other Infections | p. 104 |
Review Test | p. 109 |
Virology | p. 121 |
Nature of animal viruses | p. 121 |
Viral replication and genetics | p. 123 |
Viral pathogenesis | p. 127 |
Host defenses to viruses | p. 131 |
Immunotherapy, antivirals, and interferon (IFN) | p. 133 |
Diagnostic virology | p. 137 |
DNA viruses | p. 139 |
Positive-sense RNA viruses | p. 148 |
Negative-sense RNA viruses | p. 156 |
Other RNA viruses | p. 162 |
Slow viruses and prions | p. 164 |
Oncogenic viruses | p. 165 |
Review test | p. 169 |
Mycology | p. 173 |
Fungi | p. 173 |
Fungal diseases--overview | p. 175 |
Superficial mycoses | p. 179 |
Cutaneous mycoses | p. 179 |
Subcutaneous mycoses | p. 182 |
Fungal pneumonias and systemic mycoses | p. 182 |
Opportunistic mycoses | p. 186 |
Review chart | p. 191 |
Review test | p. 194 |
Parasitology | p. 199 |
Characteristics of parasites and their hosts | p. 199 |
Protozoan parasites | p. 199 |
Trematodes | p. 205 |
Cestodes | p. 207 |
Nematodes | p. 209 |
Review test | p. 214 |
Immunology | p. 217 |
Overview | p. 217 |
Antigens (Immunogens) | p. 219 |
Antibodies (Immunoglobulins) | p. 219 |
Immunoglobulin genetics | p. 224 |
Antigen-antibody reactions | p. 225 |
Immunocompetent cells in the immune response | p. 229 |
Actions and products of immune system cells | p. 233 |
Initiators of the immune response | p. 236 |
Immunology of acquired immunodeficiency syndrome (AIDS) | p. 237 |
Histocompatibility antigens | p. 241 |
Tumor immunology | p. 243 |
Blood group immunology | p. 244 |
The complement system | p. 245 |
Hypersensitivity reactions | p. 247 |
Developmental immunologic disorders | p. 250 |
Autoimmune disorders | p. 252 |
Review test | p. 257 |
Comprehensive Examination | p. 267 |
Index | p. 295 |
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