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A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications
The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms.
With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book:
Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.
Gary S. Stein, PhD, is the Director of the University of Vermont Cancer Center and the Perelman Professor and Chair of the Department of Biochemistry at the University of Vermont Larner College of Medicine. He is a Professor of Surgery and the Co-Director of the Northern New England Clinical and Translational Research Network.
Kimberly P. Luebbers, MSHS, RN, BSN, OCN, is the Assistant Dean for Clinical Research Administration overseeing the Office of Clinical Trials Research and administration of the Clinical Research Center, University of Vermont Larner College of Medicine.
List of Contributors ix
Preface xv
Part I: Cancer and the Cancer Experience 1
1 Cancer and the Cancer Experience 3Gary S. Stein and Kimberly P. Luebbers
Part II: Current Understanding of Cancer Biology 13
2 Cancer Biology and Pathology 15G. Premveer Reddy, Lekkala V. Reddy, and Sahn‐Ho Kim
3 Causes of Cancer: Genetic, Epigenetic, Viral, Microenvironmental, and Environmental Contributions to Cancer 53Michaela Reagan
Part III: A Cancer Diagnosis 75
4 Early Warning Signs 77Solomon A. Graf and F. Marc Stewart
5 Importance of Imaging for Diagnosis and Treatment of Cancer 89Kristin DeStigter, Sally Herschorn, Anant Bhave, Benjamin Lange, and Sean Reynolds
6 Cancer Biomarkers 107Robert H. Getzenberg
7 Molecular Diagnosis 123Mark F. Evans
Part IV: Navigating the Cancer Experience 145
8 Navigating the Cancer Experience 147David C. Nalepinski
Part V: Clinical Dimensions to Cancer 167
9 Classification of Tumors, Their Frequency and Progression 169Richard C. Zieren, Liang Dong, Sarah R. Amend, and Kenneth J. Pienta
10 Cancer Epidemiology: Identifying Cancer Risk 213Bernard F. Cole, Brian L. Sprague, Thomas P. Ahern, and Judy R. Rees
Part VI: Tumor Types 227
11 Breast Cancer: Unique Characteristics as Targets for Therapy 229Ogheneruona Apoe, Ted James, Gabriella Szalayova, Amrita Pandit, and Marie E. Wood
12 Prostate Cancer 245David W. Sobel and Mark K. Plante
13 Gastrointestinal Cancer 259Kristina Guyton, Baddr Shakhsheer, and Neil Hyman
14 Lung Cancer 271Farrah B. Khan, C. Matthew Kinsey, and Garth Garrison
15 Pediatric Oncology 285Jessica L. Heath
16 Leukemia, Lymphoma, and Myeloma 299Alan Rosmarin
17 GU Oncology: Kidney, Urothelial, and Penile Cancer 317Scott Perrapato
18 Liver Cancer: Hepatocellular Carcinoma 327Jennifer LaFemina, Bradley Switzer, and Giles F. Whalen
19 GYN Oncology: Unique Characteristic Targets for Therapy in Gynecologic Cancers 345Celeste Straight, Leslie Bradford, and Susan Zweizig
20 Testicular Cancer 365Christopher B. Allard and Michael L. Blute
21 Head and Neck Cancer 379Kumar G. Prasad, Marion Couch, and Michael Moore
22 Brain and Spinal Cord Tumors 395Lawrence Recht
23 Thyroid Cancer 415Frances E. Carr
Part VII: Treatment Options 445
24 Radiation Therapy 447Thomas J. FitzGerald, Maryann Bishop‐Jodoin, Fran Laurie, Christopher Riberdy, Jesse N. Aronowitz, Elizabeth Bannon, Bruce A. Bornstein, Carla D. Bradford, Harry Bushe, Maria G. Cicchetti, Linda Ding, Jonathan M. Glanzman, David J. Goff, Beth B. Herrick, Jessica R. Hiatt, I‐Lin Kuo, Yuan‐Chyuan Lo, Janaki Moni, Richard S. Pieters, Paul S. Rava, Allison Sacher, Jonathan Saleeby, Shirin Sioshansi, Kenneth Ulin, John M. Varlotto, and Tao Wang
25 Radiation Therapy – The Patient Experience 463Harold James Wallace, III
26 Pain Management in Cancer 481Carlos A. Pino
27 Complementary and Alternative Medicine 499Phil Trabulsy
28 Gene Therapy 531Mai K. ElMallah, Michael Kalfopolous, and Terence R. Flotte
Part VIII: Patient Resources 553
29 Cancer‐Center‐Based Care 555George J. Weiner
30 Supportive Care 563Kathleen McBeth
31 Investigating Cancer Sentiments across Social Media 573Eric M. Clark, W. Christian Crannell, Jesse Moore, Ted James, Mitchell Norotsky, and Chris A. Jones
Part IX: The Path to Reducing the Cancer Burden: Prevention, Early Detection, Recovery, Survivorship 591
32 Cancer Genetics: Risk Assessment 593Wendy McKinnon
33 Cancer Prevention: Diet, Nutrition, and Lifestyle 603Jennifer L. May and Jean R. Harvey
34 Cancer Survivorship 617David Cranmer
35 The Tools of Advocacy in Cancer Prevention, Early Detection, Recovery, and Treatment 621Jill Sudhoff‐Guerin
Index 637
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The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.