Cancer Systems Biology

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  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2010-05-04
  • Publisher: CRC Press

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This unique book introduces the concepts and theories of systems biology and applications of systems biology in cancer research.

Table of Contents

Forewordp. xi
Prefacep. xiii
About the Editorp. xv
Contributorsp. xvii
Cancer Systems Biology: Concepts and Applications
A Roadmap of Cancer Systems Biologyp. 3
Network Biology, the Framework of Systems Biologyp. 23
Reconstructing Gene Networks Using Gene Expression Profilesp. 35
Understanding Cancer Progression in Protein Interaction Networksp. 53
From Tumor Genome Sequencing to Cancer Signaling Mapsp. 69
Ubiquitin-Mediated Regulation of Human Signaling Networks in Normal and Cancer Cellsp. 91
microRNA Regulation of Networks of Normal and Cancer Cellsp. 107
Network Model of Survival Signaling in T-Cell Large Granular Lymphocyte Leukemiap. 125
Cancer Metabolic Networks: Metabolic Pathways Modeling and Metabolomics in Cancer Researchp. 143
Warburg Revisited: Modeling Energy Metabolism for Cancer Systems Biologyp. 165
Cancer Gene Prediction Using a Network Approachp. 191
Cancer Biology: Basic Concepts and Cutting-Edge Topics
Cancer Genomics to Cancer Biologyp. 215
Epithelial-to-Mesenchymai Transition (EMT): The Good, the Bad, and the Uglyp. 233
Tumors and Their Microenvironmentsp. 261
Tumor Angiogenesis: Cell-Microenvironment Interactionsp. 283
Data Resources and Software Tools for Cancer Systems Biology
Modeling Tools for Cancer Systems Biologyp. 305
Advanced Visualization, Analysis, and Inference of Biological Networks Using VisANTp. 323
Gene Set and Pathway-Based Analysis for Cancer Omicsp. 351
SH2 Domain Signaling Network and Cancerp. 367
Data Sources and Computational Tools for Cancer Systems Biologyp. 383
Indexp. 395
Table of Contents provided by Ingram. All Rights Reserved.

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