Capitalizing on New Needs and New... | Buy

This report addresses a topic of recognized policy concern. To capture the benefits of substantial U.S. investments in biomedical R&D, parallel investments in a wide range of seemingly unrelated disciplines are also required. This report summarizes a major conference that reviewed our nationrs"s R&D support for biotechnology and information technologies. The volume includes newly commissioned research and makes recommendations and findings concerning the important relationship between information technologies and biotechnology. It emphasizes the fall off in R&D investments needed to sustain the growth of the U.S. economy and to capitalize on the growing investment in biomedicine. It also encourages greater support for inter-disciplinary training to support new areas such as bioinformatics and urges more emphasis on and support for multi-disciplinary research centers.

Preface

1

(14)

Executive Summary

14

(7)

I. INTRODUCTION AND OVERVIEW

21

(12)

II. ISSUES IN BIOTECHNOLOGY AND INFORMATION TECHNOLOGY

33

(18)

III. FINDINGS AND RECOMMENDATIONS

51

(20)

IV. PROCEEDINGS

71

(24)

Welcome

73

(3)

Dale Jorgenson

Introduction

76

(2)

Bill Spencer

Opening Remarks

78

(6)

Congressman Sherwood Boehlert

Biotechnology and Information Technologies: The Need for a Diversified Federal Research Portfolio

84

(11)

Clark McFadden

Dewey Ballantine

The View From the Semiconductor and Biotechnology Industries

85

(10)

Gordon Moore

Edward Penhoet

Discussion

95

(50)

A Historical Perspective: Federal Partnerships in Computing and Biotechnology

98

(31)

Patrick Windham

Partnerships in the Computer Industry

98

(13)

Kenneth Flamm

Partnerships in the Biotechnology Industry

111

(5)

Leon Rosenberg

Trends in Federal Research

116

(13)

William Bonvillian

Luncheon Address: ``The Cornucopia of the Future''

120

(9)

Dan Goldin

Biotechnology: Needs and Opportunities

129

(16)

Edward Penhoet

Exploiting the Biotechnology Revolution: Training and Tools

129

(6)

Marvin Cassman

The New Frontier: Bioinformatics and the University

135

(4)

Rita Colwell

Emerging Opportunities and Emerging Gaps

139

(6)

Paula Stephan

Discussant: Greg Reyes, Schering-Plough

144

(1)

Stephen Dahms

Discussion

145

(12)

Information Technology: New Opportunities - New Needs

146

(11)

Dave Goldston

Biofutures for Multiple Missions

146

(3)

Jane Alexander

Meeting the Needs: Realizing the Opportunities

149

(3)

Paul Horn

New Information Technology Research Initiatives

152

(5)

Tom Kalil

Discussants: Charles Trimble, Trimble Navigation

155

(2)

Richard Rosenbloom

Discussion

157

(14)

Capturing New Opportunities

160

(11)

Michael Borrus

Computing and the Human Genome

160

(5)

Mark Boguski

NanoFrontiers

165

(4)

Alton Romig

Defense Interests and Applications

169

(2)

Timothy Coffey

Discussion

171

(18)

Intellectual Property and the Public Domain: Sectoral Perspectives

173

(16)

Jorge Goldstein

Stern

Kessler

Goldstein

Fox

Sectoral Variations in the Role of Intellectual Property

174

(5)

Wesley Cohen

Post Bayh-Dole University-Industry Relationships

179

(4)

Maryann Feldman

Intellectual Property and Biotechnology

183

(6)

Robert Blackburn

Discussion

189

(4)

Concluding Remarks

191

(2)

Gordon Moore

V. RESEARCH PAPERS

193

(126)

The Federal Partnership with U.S. Industry in U.S. Computer Research: History and Recent Concerns

195

(28)

Kenneth Flamm

Public Research, Patents, and Implications for Industrial R&D in the Drug, Biotechnology, Semiconductor and Computer Industries

223

(21)

Wesley M. Cohen

John Walsh

Bioinformatics: Emerging Opportunities and Emerging Gaps

244

(17)

Paula E. Stephan

Grant Black

Recent Trends in the Federal Funding of Research and Development Related to Health and Information Technology

261

(58)

Michael McGeary

McGeary

Smith

VI. ANNEX

319

Biographies of Contributors

321

Participants List

327

Bibliography

335

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