Cardiac Resynchronization Therapy

by St John Sutton; Martin G.

• ISBN13: 9781841846378
• ISBN10: 1841846376
• Edition: 1st
• Format: Hardcover
• Copyright: 2007-09-19
• Publisher: CRC Press

Summary

Cardiac resynchronization therapy (CRT) is one of the most exciting new advances in the treatment of chronic severe heart failure associated with dyssynchronous ventricular contraction that is refractory to medical treatment. This new text is edited by 5 experts in heart failure, electrophysiology, and non-invasive cardiac imaging, and is extensively illustrated with high quality figures and examples of clinical cases. The purpose of the book is to put into perspective this novel therapy with regards to traditional heart failure treatment and to provide criteria for the identification of patients likely to have an optimal and sustained response to CRT using a practical approach. This text begins by describing the background and evolution of the technique to the current implementation and the impact of complications on clinical outcome. There are chapters describing cutting-edge Doppler echocardiography for assessing dyssynchrony, reverse remodeling, and triaging patients into those with greatest likelihood ofresponding to CRT with illustrative clinical case examples. There is a full description of the results of all the randomized clinical trials and a number of chapters discussing the need for concomitant internal cardiac defibrillator (ICD), special circumstances such as atrial fibrillation, right bundle branch block, left ventricular lead placement, and the etiology of heart failure with clinical case examples for each.

Table of Contents

Heart failure: pathophysiology and treatment

Epidemiology of Heart Failure

The Desynchronized Heart

Conventional Medical Therapy for HF with Low EF

Determinants of Remodeling

Summary of all the Large Randomized Trials

Exploring subpopulations using CRT

Effects of CRT on Structural and Functional Remodeling

Non-responders and Patient Selection from a Heart Failure Perspective

CRT: anatomical considerations, implantation and settings

Anatomy of the Coronary Sinus

Implantation of Cardiac Resynchronization Devices

AV Optimization with CRT

V/V Optimization with CRT

Complications of CRT

Non-responders and Patient Selection from an Electrophysiology Perspective

Patient selection and follow-up; role of echocardiography

Differential Effects of CRT in Ischemic versus Non-ischemic Heart Failure

Pathobiology of left ventricular dyssynchrony

Left ventricular dyssynchrony in predicting response and patient selection; role of tissue Doppler imaging

How to Measure Response to CRT

Impact of CRT on Mitral Regurgitation

Non-responders and Patient Selection from an Echo Perspective

CRT: evolving indications and future perspectives

CRT Combined with ICD Placement?

Efficacy of CRT in Atrial Fibrillation

CRT in Atrioventricular Block or Symptomatic Bradycardia and Indication

CRT in RBBB

CRT in NYHA class II Heart Failure

CRT in Narrow QRS Duration (<120ms)

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