The Cardiovascular System at a Glance

by Aaronson, Philip I.; Ward, Jeremy P. T., Ph.D.; Wiener, Charles M., M.D.; Schulman, Steven P.; Gill, Jaswinder S.

• ISBN13: 9780632049714
• ISBN10: 0632049715
• Format: Paperback
• Copyright: 1999-06-01
• Publisher: John Wiley & Sons Inc

Summary

The Cardiovascular System At a Glance combines the concise style of the 'At a Glance' series with a systemic approach in line with the new teaching programs now in place at most medical schools around the world.The text progresses from basic science to clinical application: a general introduction to the cardiovascular system is followed by anatomy and histology; blood and body fluids; biochemistry and excitation-contraction coupling; form and function; integration and regulation; pathology and therapeutics; and case studies.The five authors, from St Thomas' and Guy's (London) and John Hopkins (Baltimore), have between them more than 40 years' experience in teaching the cardiovascular system, and have all been instrumental in the move from subject- to system-based learning at their medical schools.This book will be of interest to medical students at all levels and to students of other health professions needing an introduction to the cardiovascular system.

Table of Contents

Preface	4	(1)
Sources of illustrations	5	(1)
Introduction
Overview of the cardiovascular system	6	(2)
Anatomy and histology
Gross anatomy and histology of the heart	8	(2)
Vascular anatomy	10	(2)
Vascular histology and smooth muscle cell ultrastructure	12	(2)
Blood and body fluids
Constituents of blood	14	(2)
Erythropoiesis, haemoglobin and anaemia	16	(2)
Haemostasis and thrombosis	18	(2)
Blood groups and transfusions	20	(2)
Biochemistry and cellular physiology
Membrane potential, ion channels and pumps	22	(2)
Electrophysiology of cardiac muscle and the origin of the heart beat	24	(2)
Excitation--contraction coupling in cardiac muscle cells	26	(2)
Vascular smooth muscle excitation--contraction coupling	28	(2)
Form and function
Cardiac cycle	30	(2)
Control of cardiac output and Starling's Law of the Heart	32	(2)
Electrical conduction system in the heart	34	(2)
The electrocardiogram	36	(2)
Haemodynamics	38	(2)
Blood pressure and flow in the arteries and arterioles	40	(2)
The microcirculation and the lymphatic system	42	(2)
Fluid filtration in the microcirculation	44	(2)
The venous system	46	(2)
Local control of bloodflow	48	(2)
Regulation of the vasculature by the endothelium	50	(2)
The coronary, skeletal muscle, cutaneous and cerebral circulations	52	(2)
The pulmonary and fetal circulations	54	(2)
Integration and regulation
Cardiovascular reflexes	56	(2)
Autonomic control of the cardiovascular system	58	(2)
The control of blood volume	60	(2)
Cardiovascular effects of exercise	62	(2)
Shock and haemorrhage	64	(2)
Pathology and therapeutics
Risk factors for cardiovascular disease	66	(2)
Clinical measurement of cardiac and vascular function	68	(2)
Hyperlipidaemias	70	(2)
Atherosclerosis	72	(2)
Diagnosis and treatment of hypertension	74	(2)
Mechanisms of primary hypertension	76	(2)
Stable and variant angina	78	(2)
Unstable angina and revascularization	80	(2)
Pharmacological management of angina	82	(2)
Pathophysiology of acute myocardial infarction	84	(2)
Clinical aspects of acute myocardial infarction	86	(2)
Emerging approaches to therapy of coronary artery disease	88	(2)
Chronic heart failure	90	(3)
Treatment of chronic heart failure	93	(3)
Mechanisms of arrhythmia	96	(2)
Specific arrhythmias	98	(2)
Antiarrhythmic drugs	100	(2)
Diseases of the aortic valve	102	(2)
Diseases of the mitral valve	104	(2)
Congenital heart disease	106	(2)
Cardiac transplantation	108	(2)
Case studies: diagnosis, treatment, result
Case study: heart failure	110	(2)
Case study: valvular heart disease	112	(2)
Case study: ischaemic heart disease	114	(2)
Case study: arrhythmias	116	(3)
Index	119