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9783764358525

CELLULAR MECHANISMS IN AIRWAYS INFLAMMATION

by ; ;
  • ISBN13:

    9783764358525

  • ISBN10:

    3764358521

  • Format: Hardcover
  • Copyright: 2000-10-01
  • Publisher: Birkhauser

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Summary

Airways inflammation is a complex biological phenomenon resulting fromthe recruitment and activation of numerous cell types. Airwaysinflammation contributes to the pathophysiology of airways disease. Anunderstanding of the mechanisms that regulate inflammatory cell functionis essential for the development of novel anti-inflammatory drugs forthe treatment of common respiratory diseases such as asthma and COPD.This book provides a collection of valuable reviews on the majorinflammatory cells involved in airways disease and examines thepharmacology of current anti-inflammatory drugs used in the treatment ofairways disease. Moreover, an insight into the development of emergingdrug therapies is also highlighted.This book is a must for the library of any researcher or clinicianinterested in the pathophysiology of airways disease.

Table of Contents

List of contributors
vii
Preface xi
Pathological spectrum of airway inflammation
1(52)
Peter K. Jeffery
Role of basophils in airways inflammation
53(26)
Gianni Marone
Massimo Triggiani
Giuseppe Spadaro
Anna Maria Onorati
Arturo Genovese
Platelets
79(46)
Paolo Gresele
Roberta Vezza
Neutrophils
125(22)
Moira Whyte
Eosinophils in asthma
147(12)
Anthony J. Coyle
Jose Carlos Gutierrez-Ramos
Fibroblasts and myofibroblasts
159(40)
Ian A. Akers
Robin J. McAnulty
Geoffrey J. Laurent
Airway macrophages and dendritic cells
199(24)
Elaine Lee
Stephen A. Kilfeather
Contribution of endothelial cells to airway inflammation
223(22)
Anne Burke-Gaffney
Paul G. Hellewell
Airway epithelial cells
245(18)
Jagdish Laxman Devalia
Jia Hua Wang
Robert James Davies
Airway Smooth muscle cells
263(40)
Alastair G. Stewart
Darren J. Fernandes
Valentina Koutsoubos
Aurora Messina
Claire E. Ravenhall
Ross Vlahos
Kai-Feng Xu
Drugs that reduce airways inflammation
303(30)
Katherine H. Banner
Domenico Spina
Clive P. Page
T cells in the lung
333(24)
David M. Kemeny
Brian J. O'Connor
Index 357

Supplemental Materials

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