Chesley's Hypertensive Disorders in Pregnancy

by Roberts; Cunningham; Lindheimer

• ISBN13: 9780123742131
• ISBN10: 0123742137
• Edition: 3rd
• Format: Hardcover
• Copyright: 2009-04-24
• Publisher: Elsevier Science

Summary

Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this the hypertensive disorders remain marginally studied and management is often controversial. Chesley's Hypertensive Disorders in Pregnancy, remains one of the beacons to guide this field, recognized for its uniqueness and utility. The Third Edition continues this tradition, focusing on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, and not just preeclampsia. NEW TO THE THIRD EDITION: * New chapters focusing on recent discoveries in angiogenesis, auto-antibodies and other recent immunological findings, imaging in eclampsa, animal models - where considerable progress has emerged since the previous edition * Extensive updates to chapters on epidemiology, etiological considerations, pathophysiology, prediction, prevention, and management * Systematic reviews and metanalysis of trials regarding prediction and antihypertensive treatment * Discussions on the emerging roles of metabolic syndrome and obesity and the increasing incidence of preeclampsia * Epodemiological coverage of preeclampsia as a risk factor for future metabolic and cardiovascular disease that permits early intervention and life style changes

Table of Contents

The Clinical Spectrum of Preeclampsia

Epidemiology of Hypertension

Genetic Factors in the Etiology of Preeclampsia/Eclampsia

The Placenta in Normal Pregnacy and Preeclampsia

Angiogenesis and Preeclampsia

Metabolic Syndrome and Preeclampsia

Immunology of Normal Pregnancy and Preeclampsia

Endothelial Cell Dysfunction and Oxidative Stress

Animal Models

Tests to Predict Preeclampsia

Prevention of Preeclampsia and Eclampsia

The Brain

Cardiovascular Alterations in Normal and Preeclamptic Pregnancy

Normal and Abnormal Volume Homeostasis

Agonistic Autoantibody-Mediated Disease

The Kidney in Normal Pregnancy and Preeclampsia

Platelets, Coagulation, and the Liver

Chronic Hypertension and Pregnancy

Anti-hypertensive Treatment

Management

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