Childhood Onset of Adult Psychopathology Clinical & Research Advances

by Rapoport, Judith L.

• ISBN13: 9780880488211
• ISBN10: 0880488212
• Edition: 1st
• Format: Hardcover
• Copyright: 2000-01-01
• Publisher: AMERICAN PSYCHIATRIC PUBLISHING INC

Summary

This book provides an understanding of the childhood onsets of adult psychiatric disorders, including when and in what sequence psychiatric disorders begin in childhood, and how these disorders evolve over the life span. The authors review the data on very early forms of depression, criminality, alcoholism, schizophrenia, and anxiety.

Author Biography

Judith L. Rapoport, M.D. is Chief of the Child Psychiatry Branch at the National Institute of Mental Health in Bethesda, Maryland. Dr. Rapoport is a graduate of Swarthmore College and Harvard Medical school. Her clinical training was at the Massachusetts Mental Health Center, and at Children's Hospital in Washington, DC. Her research training was at the Karolinska Hospital in Stockholm and the Laboratory of Psychology at the National Institute of Mental Health (NIMH). Her research has covered several aspects of child psychiatry including diagnosis, childhood hyperactivity, pediatric psychopharmacology and author of three professional books and over two hundred research journal articles. She is currently Chief of the Child Psychiatry Branch, National Institute of Mental Health. Work in her branch on Attention Deficit Hyperactivity Disorder has recently focused on normal and abnormal brain development.

Table of Contents

Contributors	ix
Introduction	xiii
I Age at Onset: Mechanisms and Methods
Genetics of Early-Onset Manic-Depressive Illness and Schizophrenia	3	(24)
Judith A. Bandar
Sevilla D. Detera-Wadleigh
Elliot S. Gershon
Genetics, Evolution, and Age at Onset of Disease	27	(14)
Barton Childs
Trinucleotide Expansion in the FMRI Gene and Fragile X Syndrome	41	(24)
Stephanie Ceman
Stephen T. Warren
II Neurodevelopmental Pathways to ``Adult'' Psychiatric Disorders: Triggers of Disease Onset
Biological Markers as Precursors to Schizophrenia: Specificity, Predictive Ability, and Etiological Significance	65	(38)
C. Jane Tarrant
Peter B. Jones
PANDAS : A New ``Species'' of Childhood-Onset Obsessive-Compulsive Disorder?	103	(18)
Susan E. Swedo
Margaret Pekar
Prenatal Antecedents of Neuropsychiatric Disorder Over the Life Course: Collaborative Studies of United Birth Cohorts	121	(28)
Ezra Susser
Alan Brown
Tom Matte
III Schizophrenia: Specific Disorders
Late-Onset Schizophrenia: New Insights Into Disease Etiology	149	(18)
Lisa T. Eyler Zorrilla
Dilip V. Jeste
Childhood-Onset Schizophrenia: What Can It Teach Us?	167	(26)
Rob Nicolson
Judith L. Rapoport
Neurodevelopmental Hypothesis of Schizophrenia 12 Years On: Data and Doubts	193	(30)
Colm McDonald
Paul Fearon
Robin Murray
IV Depression and Anxiety
Childhood Depression: Is It the Same Disorder?	223	(22)
Richard Harrington
Offspring at Risk: Early-Onset Major Depression and Anxiety Disorders Over a Decade	245	(14)
Myrna M. Weissman
Virginia Warner
Priya Wickramaratne
Donna Moreau
Mark Olfson
When Is Onset? Investigations Into Early Developmental Stages of Anxiety and Depressive Disorders	259	(44)
Hans-Ulrich Wittchen
Roselind Lieb
Peter Schuster
Albertine J. Oldehinkel
Very-Early-Onset Bipolar Disorder: Does It Exits?	303	(30)
Gabrielle A. Carlson
V Early Prevention of Adult Psychiatric Disorders
Prevention of Mental Disorders and the Study of Developmental Psychopathology: A Natural Alliance	333	(24)
William R. Beardslee
Prevention of Alcoholism: Reflections of a Naturalist	357	(22)
George E. Vaillant
Prevention of Antisocial Personality Disorder	379	(20)
David R. Offord
Index	399