Classics in Stereoselective Synthesis

by Carreira, Erick M.; Kvaerno, Lisbet

• ISBN13: 9783527299669
• ISBN10: 3527299661
• Edition: 1st
• Format: Paperback
• Copyright: 2009-02-09
• Publisher: Wiley-VCH

Summary

Providing an excellent compilation of the most important and useful methods of modern stereoselective synthesis, this book features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the users' own synthesis. The authors adopt a novel approach in not attempting to present this rapidly developing area in its entirety, but to distill the truly groundbreaking reactions that should be in the repertoire of every synthetic organic chemist.

Author Biography

Professor Carreira obtained his Ph.D. degree in 1990 from Harvard University and became Assistant Professor at the same faculty in 1992. After becoming full professor in 1997 he moved to ETH Z++rich in 1998. He is recipient of many awards among them the Nobel Laureate Signature Award and the ACS Award in Pure Chemistry. His research focuses on asymmetric synthesis of natural products.

Dr. Lisbet Kvaerno received her PhD in 2004 and worked as a Postdoc at the ETH Zuerich, Switzerland in the group of Erick M. Carreira. After a second postdoctoral stay at Harvard in he group of David A. Evans she moved to Germany where she is currently an Independent Junior Group Leader at the Max Planck Institute of Coal Research. Research in her group is focused on organic synthesis and the discovery of new reaction methodology, in particular stereoselective and catalytic asymmetric reactions.

Table of Contents

Macrocyclic Stereocontrol Carbony

l Addition Reactions alpha-Functionalization of Enolates Aldol Reactions Allylations of C=O Bonds Chiral

Acetals Alkene

Hydroboration Reductions of Olefins

Oxidations of Olefins

Amino Acids Additions to C=N Bonds

Conjugate Additions Chiral Carbanions

Metal-Catalyzed Allylations

Cyclopropanations and CH-Insertion

Reactions Sigmatropic Rearrangements

Diels-Alder and Hetero-Diels-Alder

Reactions [3+2]- and [2+2]-Cycloaddition Reactions

Table of Contents provided by Publisher. All Rights Reserved.