Clinical Management of Renal Tumors

by Bukowski, Ronald M.; Novick, Andrew C.

• ISBN13: 9781588292513
• ISBN10: 1588292517
• Edition: 1st
• Format: Hardcover
• Copyright: 2008-03-30
• Publisher: Humana Pr Inc

Summary

This volume provides an in-depth review of the data relating to the management of renal tumors as well as an updated description regarding pathologic and molecular classification of renal tumors. The neoplasms covered include clear cell carcinomas, papillary cancers, nonepithelial tumors, and other mass lesions that resemble tumors. The management of patients with renal cancer having localized or advanced disease are discussed. Surgical approaches for primary and metastatic tumors, symptom palliation, and systemic therapy for metastatic disease including immunotherapy and targeted approaches are discussed in detail.

Table of Contents

Preface	p. vii
Contributors	p. xiii
List of Color Plates	p. xvii
Renal Cell Carcinoma: Background	p. 1
Imaging of Renal Cell Carcinoma	p. 9
The Role of Percutaneous Imaging-Guided Biopsy in the Diagnosis and Management of Renal Masses	p. 43
Pathology of Renal Cell Carcinomas	p. 55
Epidemiology of Renal Tumors	p. 73
Molecular Genetics in Inherited Renal Cell Carcinoma: Identification of Targets in the Hereditary Syndromes	p. 97
T-Cell Unresponsiveness in Renal Cell Carcinoma Patients	p. 115
Renal Cell Carcinoma: Clinical Presentation and Diagnosis	p. 131
Clinical and Pathologic Staging of Renal Cell Carcinoma	p. 145
Active Surveillance of Localized Renal Tumors	p. 159
Radical Nephrectomy	p. 177
Laparoscopic Radical Nephrectomy	p. 195
Open Nephron-Sparing Surgery for Renal Cell Carcinoma	p. 205
Minimally Invasive Nephron-Sparing Surgery for Renal Tumors: Laparoscopic Partial Nephrectomy and Probe Ablative Treatments	p. 219
The Role of Angioinfarction in the Management of Renal Tumors	p. 247
Surveillance Strategies Following Curative Therapy for Localized Renal Cell Carcinoma	p. 265
Local Recurrence of Renal Cell Carcinoma: Management	p. 275
Adjuvant Therapy of Renal Cell Carcinoma	p. 293
Prognostic Factors for Survival in Metastatic Renal Cell Carcinoma	p. 307
Functional Imaging of Renal Cell Carcinoma	p. 323
Nephrectomy in Patients with Metastatic Renal Cell Carcinoma: Clinical and Biologic Effects	p. 335
Spontaneous Regression of Renal Cell Carcinoma and the Role of Prognostic Factors	p. 355
Systemic Therapy for Metastatic Renal Cell Carcinoma: Cytokines	p. 367
Chemotherapy for Metastatic Clear-Cell Renal Cell Carcinoma	p. 385
Signal Transduction Inhibitors in Renal Cell Carcinoma	p. 399
Pulmonary Metastases in Patients with Advanced Renal Cell Carcinoma: Role of Metastasectomy	p. 415
Management of Skeletal Metastases in Renal Cell Carcinoma Patients	p. 421
Renal Cell Carcinoma Metastatic to the Pancreas: Clinical and Therapeutic Aspects	p. 461
Intracranial Renal Cell Cancer Metastasis	p. 481
Role of Radiation Therapy in Advanced Renal Cell Carcinoma	p. 497
Palliation in Renal Cancer	p. 507
Management of Patients with Pathologic Variants of Renal Cell Carcinoma: Papillary, Collecting Duct, Medullary and Chromophobe Carcinoma, and Sarcomatoid Differentiation	p. 529
Renal Cell Carcinoma in Patients with End-Stage Renal Disease	p. 545
Management of Renal Adenomas and Oncocytomas	p. 555
Renal Angiomyolipoma: Diagnosis and Management	p. 565
Transitional Cell Carcinoma of the Renal Pelvis: Management	p. 587
Wilms' Tumor in Children and Adults	p. 599
Rare Malignancies of the Kidney: Evaluation and Management	p. 617
Index	p. 637
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