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Avram H. Mack, M.D., is Attending Physician at Georgetown University Hospital, Washington, D.C., and Associate Professor of Clinical Psychiatry at Georgetown University School of Medicine in Washington, D.C.
Amy L. Harrington, M.D., is Physician at Georgetown University Hospital in Washington, D.C.
Richard J. Frances, M.D., is Clinical Professor of Psychiatry at New York University, New York City; Adjunct Professor of Psychiatry at University of Medicine and Dentistry of New Jersey, Newark, New Jersey; and Director of Professional and Public Education at Silver Hill Hospital in New Canaan, Connecticut.
Foreword | p. xi |
Preface | p. xv |
Introduction | p. 1 |
Treatment of Substance Use Disorders: General Tenets | p. 3 |
Therapeutic Alliance | p. 5 |
Potential Abuses in the Treatment of Substance Use Disorders | p. 7 |
Key Points | p. 8 |
References | p. 8 |
Magnitude of the Problem | p. 11 |
General Epidemiology | p. 11 |
Substances of Abuse and Misuse | p. 14 |
Underlying Issues Affecting Addiction Magnitude | p. 24 |
Factors Contributing to Complications | p. 25 |
Key Points | p. 27 |
References | p. 28 |
Neurobiology of Addictive Disorders and the Disease Concept | p. 31 |
Nosology | p. 33 |
Neurobiology of the Addictions: Clinical Implications of Research Findings | p. 33 |
Key Points | p. 40 |
References | p. 40 |
Evaluation and Assessment | p. 43 |
A Moving Target | p. 43 |
Admission Workup | p. 44 |
Specific Substance Use History-Taking | p. 44 |
Diagnostic Instruments | p. 46 |
Laboratory Evaluations | p. 52 |
Imaging Studies | p. 60 |
Key Points | p. 61 |
References | p. 61 |
Definition, Presentation, and Diagnosis | p. 63 |
Nosology | p. 63 |
DSM-IV Context | p. 64 |
Generic Definitions and Diagnosis | p. 64 |
Alcohol | p. 69 |
Sedatives, Hypnotics, and Anxiolytics | p. 74 |
Opioids | p. 76 |
Cocaine | p. 77 |
Amphetamines | p. 81 |
Phencyclidine and Ketamine | p. 82 |
Hallucinogens | p. 83 |
Cannabis | p. 85 |
Nicotine | p. 87 |
Inhalants | p. 89 |
Caffeine | p. 90 |
Other (or Unknown) Substance-Related Disorders | p. 91 |
Polysubstance Dependence | p. 91 |
Establishing a Diagnosis: Dilemmas, Signs, and Countertransference | p. 92 |
Psychiatric Comorbidity | p. 94 |
Key Points | p. 98 |
References | p. 98 |
Natural Histories of Substance Abuse | p. 101 |
Alcohol | p. 101 |
Sedatives, Hypnotics, and Anxiolytics | p. 105 |
Opioids | p. 106 |
Cocaine | p. 108 |
Amphetamines | p. 110 |
Phencyclidine and Ketamine | p. 111 |
Hallucinogens | p. 111 |
Cannabis | p. 112 |
Nicotine | p. 114 |
Inhalants | p. 116 |
Key Points | p. 117 |
References | p. 117 |
Violence and Suicide, Injury, Corrections, and Forensics | p. 121 |
Violence and Crime | p. 121 |
Suicide | p. 122 |
Unintentional Injury | p. 126 |
Correctional Settings | p. 127 |
Forensic Practice | p. 129 |
Key Points | p. 132 |
References | p. 132 |
Behavioral Addictions | p. 135 |
Basis of Overlap Among Addictions | p. 136 |
Epidemiology | p. 136 |
Etiology and Neurobiology | p. 137 |
Pathological Gambling | p. 137 |
Kleptomania | p. 139 |
Compulsive Buying | p. 140 |
Key Points | p. 141 |
References | p. 141 |
Children and Adolescents | p. 145 |
Extent of the Problem | p. 146 |
Early Detection in Adolescents | p. 146 |
Contributing Factors | p. 146 |
Role of Families in Treatment | p. 147 |
Residential Treatment | p. 148 |
Substance Intoxication or Psychosis | p. 148 |
Mentally III, Chemically Abusing Adolescents | p. 149 |
Assessment | p. 150 |
Clinical Management Issues | p. 150 |
Psychopharmacology | p. 151 |
Relapse Prevention | p. 151 |
Primary, Secondary, and Tertiary Prevention | p. 152 |
Neurodevelopmental Effects of Maternal Substance Use on the Fetus | p. 153 |
Key Points | p. 155 |
References | p. 156 |
Specific Populations | p. 159 |
Women | p. 159 |
The Elderly | p. 164 |
Chronic, Disabled, and Homeless Patients | p. 166 |
Minority Populations | p. 170 |
Key Points | p. 172 |
References | p. 172 |
General Hospital and Primary Care Settings | p. 175 |
The General Hospital | p. 175 |
The Outpatient Medical Setting | p. 176 |
Psychiatric Consultation to General Floors and the Emergency Department | p. 176 |
Treatment Planning | p. 178 |
Additional Treatment Issues | p. 178 |
Making the Referral to Specialty Care | p. 179 |
Issues in the Care of the Medical/Surgical Patient With a Substance Use Disorder | p. 179 |
Key Points | p. 184 |
References | p. 184 |
Treatment Modalities | p. 185 |
Psychosocial Modalities | p. 185 |
Pharmacological Modalities | p. 193 |
Key Points | p. 204 |
References | p. 204 |
Treatment Approaches | p. 209 |
Abstinence | p. 209 |
Recovery | p. 210 |
Relapse | p. 210 |
Predictors of Successful Treatment Outcome | p. 212 |
Differential Therapeutics | p. 213 |
Matching Treatments to Patients | p. 213 |
Treatment Settings | p. 214 |
Clinical Situations | p. 216 |
Withdrawal and Detoxification | p. 222 |
Special Issues in Treatment | p. 237 |
Key Points | p. 241 |
References | p. 241 |
Public Health Issues | p. 245 |
The Workplace | p. 245 |
Public Policy on Prevention and Control | p. 253 |
Public Sector Clinical Approaches | p. 255 |
Key Points | p. 258 |
References | p. 258 |
Appendix: Workplace Substance Abuse Resources | p. 261 |
Index | p. 263 |
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