Clinical MR Neuroimaging: Physiological and Functional Techniques

by Edited by Jonathan H. Gillard , Adam D. Waldman , Peter B. Barker

• ISBN13: 9780521515634
• ISBN10: 0521515637
• Edition: 2nd
• Format: Hardcover
• Copyright: 2009-12-21
• Publisher: Cambridge University Press

Summary

Clinical MR Neuroimaging, second edition, provides radiologists, neuroscientists and researchers with a clear understanding of each physiological MR methodology and their applications to the major neurological diseases. Section 1 describes the physical principles underlying each technique and their associated artefacts and pitfalls. Subsequent sections review the application of MRI in a range of clinical disorders: cerebrovascular disease, neoplasia, infection/inflammation/demyelination disorders, seizures, psychiatric/neurodegenerative conditions, and trauma. This new edition includes all recent advances and applications, with greatly increased coverage of permeability imaging, susceptibility imaging, iron imaging, MR spectroscopy and fMRI. All illustrations are completely new, taking advantage of the latest scan capabilities to give images of the highest possible quality. In addition, over 35 new case studies have been included. Editors and contributors are the leading neuroimaging experts worldwide; their unique combination of technical knowledge and clinical expertise makes Clinical MR Neuroimaging the leading text on the subject.

Table of Contents

Introduction

Physiological MR Techniques

Fundamentals of MR spectroscopy

Quantification and analysis in MR spectroscopy

Artifacts and pitfalls in MR spectroscopy

Fundamentals of diffusion MR imaging

Human white matter anatomical information revealed by diffusion tensor imaging and fiber tracking

Artifacts and pitfalls in diffusion MR imaging

Cerebral perfusion imaging by exogenous contrast agents

MRI detection of regional blood flow using arterial spin labelling

Imaging perfusion and blood-brain barrier permeability using T1-weighted dynamic contrast-enhanced MRI

Susceptibility weighted imaging

Artifacts and pitfalls in perfusion MR imaging

fMRI - methodologies, practicalities and pitfalls

Cerebrovascular Disease

Cerebrovascular disease: overview

MR spectroscopy in stroke

Diffusion and perfusion MR in stroke

Arterial spin labelling in stroke

MR diffusion tensor imaging in stroke

MR spectroscopy in severe obstructive carotid artery disease

Perfusion and diffusion imaging in chronic carotid disease

Susceptibility imaging and stroke

Adult Neoplasia

Adult neoplasia: overview

MRS in adult neoplasia

Diffusion MR imaging in adult neoplasia

Perfusion MR imaging in adult neoplasia

Permeability imaging in adult neoplasia

Functional MRI in presurgical planning

Infection, Inflammation and Demyelination

Physiological imaging in infection, inflammation and demyelination: overview

MR spectroscopy in intracranial infection

Diffusion and perfusion MR imaging of intracranial infection

MR spectroscopy in demyelination and inflammation

Diffusion and perfusion MRI in inflammation and demyelination

Physiological MR to evaluate HIV-associated brain disorders

Seizure Disorders

Seizure disorders

MR spectroscopy in seizure disorders

Diffusion and perfusion MR imaging in seizure disorders

Psychiatric and Neurodegenerative Diseases

Psychiatric and neurodegenerative disease: overview

MR spectroscopy in psychiatry

Diffusion MR imaging in neuropsychiatry and aging

1H MR spectroscopy in aging and dementia

Physiological MR in neurodegenerative diseases

Iron imaging in neurodegenerative disorders

Trauma

Potential role of MR spectroscopy, diffusion-weighted/diffusion tensor imaging and perfusion imaging in traumatic brain injury: overview

MR spectroscopy in traumatic brain injury

Diffusion and perfusion-weighted MR imaging in head injury

Susceptibility weighted imaging in traumatic brain injury

Pediatrics

Physiological MR of the pediatric brain: overview

Physiological MRI of normal development and developmental delay

MR spectroscopy in hypoxic brain injury

The role of diffusion and perfusion weighted brain imaging in neonatology

Physiological MR of pediatric brain tumors

Physiological MRI techniques and pediatric stroke

MR spectroscopy in pediatric white matter disease

MR spectroscopy of inborn errors of metabolism

Pediatric trauma

Physiological MR of the spine

Index

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