Foreword | p. 6 |
Preface | p. 7 |
Abbreviations | p. 8 |
Neurologic Diagnosis | p. 11 |
The Neurologic History | p. 11 |
Neurologic Examination | p. 13 |
Imaging the Brain | p. 23 |
Imaging the Cerebral Circulation | p. 26 |
Imaging the Spine | p. 29 |
Lumbar Puncture (LP) and Cerebrospinal Fluid (CSF) Examination | p. 31 |
Electroencephalography (EEG) | p. 33 |
Nerve Conduction Studies | p. 35 |
Electromyography (EMG) | p. 38 |
Evoked Potentials | p. 40 |
Further Reading | p. 43 |
Disorders of Consciousness | p. 44 |
Coma | p. 44 |
Brain Death | p. 51 |
Permanent Vegetative State (PVS) | p. 52 |
Locked-in Syndrome | p. 55 |
Narcolepsy | p. 56 |
Syncope | p. 59 |
Further Reading | p. 64 |
Epilepsy | p. 65 |
Epilepsy | p. 65 |
Status Epilepticus (SE) | p. 82 |
Juvenile Myoclonic Epilepsy (JME) (Janz Syndrome) | p. 86 |
Progressive Myoclonic Epilepsies (PME) | p. 87 |
Further Reading | p. 90 |
Headache | p. 91 |
Headache | p. 91 |
Migraine | p. 95 |
Muscle Contraction/Tension-type Headache | p. 101 |
Cluster Headache (Migrainous Neuralgia) | p. 103 |
Further Reading | p. 106 |
Vertigo | p. 107 |
Vertigo | p. 107 |
Benign Paroxysmal Positional Vertigo | p. 110 |
Vestibular Neuronitis | p. 111 |
Meniere's Disease | p. 111 |
Further Reading | p. 112 |
Movement Disorders | p. 113 |
Dystonia | p. 113 |
Essential Tremor | p. 119 |
Chorea | p. 122 |
Myoclonus | p. 124 |
Dyskinesias | p. 129 |
Tourette Syndrome | p. 130 |
Neuroleptic Malignant Syndrome | p. 133 |
Further Reading | p. 135 |
Developmental Diseases of the Nervous System | p. 136 |
Arnold-Chiari Malformation | p. 136 |
Rachischisis (Dysraphism) | p. 139 |
Tuberous Sclerosis | p. 143 |
Neurofibromatosis | p. 147 |
Sturge-Weber Disease (Encephalotrigeminal Vascular Syndrome) | p. 151 |
Hereditary Hemorrhagic Telangiectasia (HHT) (Osler-Rendu-Weber Syndrome) | p. 153 |
Further Reading | p. 156 |
Inherited Metabolic Diseases of the Nervous System of Adult Onset | p. 157 |
Wilson's Disease (WD) (Hepatolenticular Degeneration) | p. 157 |
Hallervorden-Spatz Disease | p. 162 |
Mitochondrial (Oxidative Phosphorylation) Diseases | p. 162 |
Adrenoleukodystrophy (ALD) | p. 166 |
Metachromatic Leukodystrophy (MLD) | p. 169 |
Adult-onset Globoid Cell Leukodystrophy (Krabbe Disease) | p. 171 |
Late-onset G[subscript M2] Gangliosidosis | p. 172 |
Niemann-Pick Disease Type C (NP-C) | p. 174 |
Further Reading | p. 176 |
Traumatic Diseases of the Nervous System | p. 177 |
Subdural Hematoma | p. 177 |
Further Reading | p. 180 |
Vascular Diseases of the Nervous System | p. 181 |
Neurovascular Syndromes | p. 181 |
Transient Ischemic Attacks (TIAs) of the Brain and Eye | p. 186 |
Stroke | p. 192 |
Atherosclerotic Ischemic Stroke | p. 202 |
Cardioembolic Stroke | p. 209 |
Infective Endocarditis | p. 215 |
Antiphospholipid Syndrome and other Prothrombotic States (Thrombophilias) | p. 218 |
Dissection of the Carotid and Vertebral Arteries | p. 224 |
Central Nervous System Vasculitis | p. 227 |
Giant Cell Arteritis (GCA) | p. 234 |
Primary Intracerebral Hemorrhage (PICH) | p. 238 |
Arteriovenous Malformation (AVM) | p. 245 |
Subarachnoid Hemorrhage (SAH) | p. 249 |
Cerebral Venous Thrombosis | p. 257 |
Vascular Dementia | p. 261 |
Hypertensive Encephalopathy | p. 265 |
Pituitary Apoplexy | p. 268 |
Further Reading | p. 269 |
Infections of the Nervous System | p. 273 |
Bacterial Infections | |
Acute Pyogenic (Bacterial) Meningitis | p. 273 |
Subacute and Chronic Meningitis and/or Encephalitis | p. 279 |
Tuberculous Meningo-encephalitis | p. 281 |
Intracranial Abscess (Brain Abscess and Subdural Empyema) | p. 284 |
Tetanus | p. 287 |
Whipple's Disease | p. 289 |
Viral Infections | |
Acute Aseptic Meningitis | p. 291 |
Viral Encephalitis | p. 292 |
Herpes Simplex Virus Encephalitis (HSE) | p. 295 |
Varicella-Zoster Virus Encephalomyelitis | p. 299 |
Human Immunodeficiency Virus (HIV)-Associated Cognitive Motor Complex (HIV-CMC) | p. 301 |
Subacute Sclerosing Panencephalitis (SSPE) | p. 304 |
Progressive Multifocal Leukoencephalopathy (PML) | p. 307 |
Poliomyelitis (Infantile Paralysis) | p. 309 |
Other Infections | |
Neurosyphilis | p. 312 |
Lyme Disease (Neuroborreliosis) | p. 316 |
Cryptococcal Meningitis | p. 318 |
Mucormycosis of the Nervous System | p. 321 |
Toxoplasmic Encephalitis | p. 323 |
Cysticercosis | p. 326 |
Creutzfeldt--Jakob Disease (CJD) | p. 330 |
Further Reading | p. 335 |
Inflammatory Disorders of the Nervous System | p. 337 |
Acute Disseminated Encephalomyelitis (Post Infectious Encephalomyelitis) (ADEM) | p. 337 |
Multiple Sclerosis (MS) | p. 340 |
Neurosarcoidosis | p. 350 |
Cavernous Sinus Syndrome | p. 354 |
Further Reading | p. 356 |
Tumors of the Central Nervous System | p. 357 |
Brain Tumors | p. 357 |
Gliomas | p. 364 |
Optic Nerve Glioma | p. 372 |
Meningioma | p. 374 |
Craniopharyngioma | p. 377 |
Pituitary Tumors | p. 379 |
Acoustic Neuroma | p. 383 |
Primary CNS Lymphoma | p. 385 |
Germ Cell Tumors of the CNS | p. 388 |
von Hippel--Lindau Disease (VHL) | p. 392 |
Metastases to the CNS | p. 396 |
Paraneoplastic Syndromes | p. 401 |
Further Reading | p. 406 |
Degenerative Diseases of the Nervous System | p. 407 |
Alzheimer's Disease (AD) | p. 407 |
Frontotemporal Dementia Associated with Mutation in Tau (Pick's Disease, Lobar Atrophy) | p. 414 |
Huntington's Disease (HD) | p. 417 |
Parkinson's Disease (PD) | p. 420 |
Diffuse Lewy Body Disease (DLBD) | p. 430 |
Progressive Supranuclear Palsy (PSP) | p. 432 |
Multiple Systems Atrophy | p. 435 |
Autosomal Dominant Cerebellar Ataxias | p. 437 |
Friedreich's Ataxia | p. 441 |
Ataxia Telangiectasia (Louis--Bar Syndrome) | p. 444 |
Further Reading | p. 447 |
Acquired Metabolic Diseases of the Nervous System | p. 449 |
Hypoxic Encephalopathy | p. 449 |
Hepatic Encephalopathy (HE) | p. 452 |
Central Pontine Myelinolysis | p. 457 |
Further Reading | p. 459 |
Nutritional Deficiency and the Nervous System | p. 460 |
Wernicke--Korsakoff Syndrome | p. 460 |
Vitamin B[subscript 12] Deficiency | p. 463 |
Further Reading | p. 467 |
Disorders of the CSF Circulation | p. 468 |
Hydrocephalus | p. 468 |
Normal Pressure Hydrocephalus | p. 473 |
Idiopathic Intracranial Hypertension (IIH) (Benign Intracranial Hypertension, Pseudotumor Cerebri) | p. 477 |
Further Reading | p. 480 |
Cranial Neuropathies | p. 481 |
Olfactory (Ist Cranial Nerve) Neuropathy | p. 481 |
Optic (IInd Cranial Nerve) Neuropathy | p. 483 |
Anterior Ischemic Optic Neuropathy (AION) | p. 487 |
Optic Neuritis | p. 489 |
Leber's Hereditary Optic Neuropathy (LHON) | p. 491 |
Papilledema | p. 492 |
Horner's Syndrome | p. 494 |
Holmes--Adie Syndrome | p. 497 |
IIIrd, IVth, and VIth Cranial Nerve (Ocular Motor) Neuropathies | p. 499 |
Trigeminal (Vth Cranial Nerve) Neuropathy | p. 505 |
Trigeminal Neuralgia (Tic Douloureux, Paroxysmal Facial Pain) | p. 509 |
Facial (VIIth Cranial Nerve) Neuropathy | p. 511 |
Acute Idiopathic Facial Paralysis (Bell's Palsy) | p. 515 |
Vestibular-cochlear (VIIIth Cranial Nerve) Neuropathy | p. 517 |
IXth Cranial Nerve (Glossopharyngeal) Neuropathy | p. 520 |
Vagus (Xth Cranial Nerve) Neuropathy | p. 523 |
Spinal Accessory (XIth Cranial Nerve) Neuropathy | p. 525 |
Hypoglossal (XIIth Cranial Nerve) Neuropathy | p. 526 |
Further Reading | p. 528 |
Spinal Cord Diseases | p. 529 |
Hereditary Spastic Paraparesis | p. 529 |
Spinal Muscular Atrophy (SMA) | p. 532 |
Motor Neuron Diseases (MND) | p. 534 |
Syringomyelia | p. 541 |
Cervical Spondylotic Myelopathy and Radiculopathy | p. 545 |
Acute 'Slipped Disc' | p. 550 |
Spinal Epidural Hematoma | p. 554 |
Spinal Epidural Abscess | p. 555 |
Spinal Arachnoiditis | p. 557 |
Spinal Cord Infarction | p. 558 |
Acute Transverse Myelitis | p. 561 |
Human Immunodeficiency Virus (HIV) Myelopathy | p. 564 |
Radiation-induced Encephalo-myelo-radiculopathy | p. 565 |
Spinal Cord Tumors | p. 567 |
Further Reading | p. 572 |
Autonomic Nervous System Disorders | p. 573 |
Autonomic Neuropathy | p. 573 |
Further Reading | p. 578 |
Diseases of the Peripheral Nerve | p. 579 |
Peripheral Neuropathy | p. 579 |
Hereditary Neuropathies | p. 584 |
Hereditary Motor and Sensory Neuropathy (Charcot--Marie--Tooth Disease) | p. 585 |
Hereditary Neuropathy with Liability to Pressure Palsies (HNPP) | p. 587 |
Guillain--Barre Syndrome (GBS) (Acute Inflammatory Demyelinating Polyradiculoneuropathy [AIDP]) | p. 588 |
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) | p. 593 |
Neuralgic Amyotrophy | p. 595 |
Vasculitic Neuropathy | p. 597 |
Herpes Zoster Infection | p. 599 |
Human Immunodeficiency Virus (HIV) Neuropathy | p. 601 |
Leprosy | p. 604 |
Paraproteinemic Polyneuropathies | p. 606 |
Diabetic Neuropathy | p. 610 |
Further Reading | p. 613 |
Mononeuropathies | p. 615 |
Dorsal Scapular Nerve (to Rhomboids) Neuropathy | p. 615 |
Long Thoracic Neuropathy | p. 616 |
Suprascapular Neuropathy | p. 618 |
Axillary Neuropathy | p. 620 |
Musculocutaneous Neuropathy | p. 621 |
Radial Neuropathy | p. 623 |
Median Neuropathy | p. 627 |
Carpal Tunnel Syndrome (CTS) | p. 630 |
Ulnar Neuropathy | p. 632 |
Lateral Cutaneous Nerve of the Thigh Neuropathy | p. 637 |
Posterior Cutaneous Nerve of the Thigh Neuropathy | p. 639 |
Femoral Neuropathy | p. 640 |
Obturator Neuropathy | p. 642 |
Gluteal Neuropathy | p. 643 |
Sciatic Neuropathy | p. 644 |
Tibial Neuropathy | p. 647 |
Peroneal Neuropathy | p. 650 |
Sural Neuropathy | p. 654 |
Pudendal Neuropathy | p. 655 |
Further Reading | p. 656 |
Neuromuscular Junction Disorders | p. 657 |
Myasthenia Gravis (MG) | p. 657 |
Lambert--Eaton Myasthenic Syndrome (LEMS) | p. 664 |
Further Reading | p. 667 |
Muscle Disorders | p. 668 |
X-lined Dystrophinopathies | p. 668 |
Facio-scapulo-humeral Muscular Dystrophy (FSHD) | p. 672 |
Limb-girdle Muscular Dystrophies (LGMD) | p. 674 |
Myotonic Dystrophy | p. 678 |
Polymyositis | p. 681 |
Dermatomyositis | p. 684 |
Inclusion Body Myositis (IBM) | p. 687 |
Metabolic and Endocrine Myopathies | p. 688 |
Hypokalemic Paralysis | p. 693 |
Further Reading | p. 695 |
Index | p. 696 |
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