Comprehensive Clinical Nephrology

by Johnson, Richard J.

• ISBN13: 9780723431176
• ISBN10: 0723431175
• Format: Hardcover
• Copyright: 2000-01-01
• Publisher: Elsevier Science Health Science div

Summary

COMPREHENSIVE CLINICAL NEPHROLOGY clearly explains how to identify, treat and manage nephrologic disorders. This clinically focused, single volume text is extensively illustrated in color. Each chapter is written by an expert in the field and presents an international perspective of the subject. The first section covers examination of the patient, signs and symptoms, and modern assessment techniques. The second section is disease-based and covers the wide spectrum of cases seen in clinical practice. The consistent structure, integration of the basic science, fantastic artwork program, and clinical focus of this book make it a valuable resource for all Nephrology residents and practitioners. * Clinically focused with basic science integrated throughout reflecting the way physicians practice. * Covers all areas necessary when diagnosing, treating and managing a patient.

Table of Contents

List of Contributors	p. ix
Preface	p. xvii
Dedication	p. xvii
Essential Renal Anatomy and Physiology
Renal Anatomy	p. 1
Renal Physiology	p. 13
Investigation of Renal Disease
Assessment of Renal Function	p. 27
Urinalysis	p. 35
Imaging	p. 47
Renal Biopsy	p. 63
Fluid and Electrolyte Disorders
Disorders of Extracellular Volume	p. 71
Disorders of Water Metabolism	p. 87
Disorders of Potassium Metabolism	p. 109
Disorders of Calcium, Phosphate, and Magnesium Metabolism	p. 123
Normal Acid-Base Balance and Metabolic Acidosis	p. 141
Metabolic Alkalosis	p. 157
Respiratory Acidosis, Respiratory Alkalosis, and Mixed Disorders	p. 167
Actue Renal Failure
Clinical Evaluation, Management, and Outcome of Acute Renal Failure	p. 183
Causes of Acute Renal Failure	p. 207
Hepatorenal Syndrome	p. 225
Myeloma Kidney	p. 235
Glomerular Disease
Introduction to Glomerular Disease: Pathogenesis and Classification	p. 243
Introduction to Glomerular Disease: Clinical Presentations	p. 255
Minimal Change Disease and Primary Focal Segmental Glomerulosclerosis	p. 271
Secondary Focal Segmental Glomerulosclerosis	p. 283
Membranous Nephropathy	p. 295
Membranoproliferative Glomerulonephritis and Cryoglobulinemic Glomerulonephritis	p. 309
IgA Nephropathy and Henoch-Schonlein Nephritis	p. 319
Antiglomerular Basement Membrane Disease and Goodpasture's Syndrome	p. 331
Renal and Systemic Vasculitis	p. 341
Lupus Nephritis	p. 357
Glomerular Diseases Associated with Infection	p. 373
Renal Amyloidosis and Glomerular Diseases with Monoclonal Immunoglobulin Deposition	p. 387
Other Glomerular Disorders	p. 403
Thrombotic Microangiopathies including Hemolytic-Uremic Syndrome	p. 413
Diabetic Nephropathy
Clinical Manifestations and Natural History of Diabetic Nephropathy	p. 425
Pathogenesis, Prevention, and Treatment of Diabetic Nephropathy	p. 439
Management of End-stage Renal Disease in Diabetes	p. 451
Hypertension
Normal Blood Pressure Control and the Evaluation of Hypertension	p. 463
Pathogenesis and Clinical Course of Essential Hypertension	p. 477
Nonpharmacologic Treatment of Hypertension	p. 489
Pharmacological Treatment of Hypertension	p. 497
Renovascular Hypertension	p. 515
Endocrine Causes of Hypertension	p. 529
Neurogenic Hypertension Including Following Stroke and with Spinal Cord Injury	p. 543
Hypertension in African Americans	p. 551
Pregnancy and Renal Disease
Renal Physiology in Normal Pregnancy	p. 559
Complications in the Normal Pregnancy	p. 567
Pregnancy with Pre-Existing Renal Disease	p. 583
Hereditary and Congenital Diseases of the Kidney
Autosomal Dominant Polycystic Kidney Disease	p. 597
Other Cystic Kidney Diseases	p. 611
Alport and Other Familial Glomerular Syndromes	p. 627
Inherited Disorders of Sodium and Water Handling	p. 639
Fanconi's Syndrome and Other Proximal Tubule Disorders	p. 653
Sickle Cell Disease	p. 665
Congenital Abnormalities of the Renal Tract	p. 677
Urinary Tract Infection
Urinary Tract Infections in Adults	p. 695
Tuberculosis of the Urinary Tract	p. 707
Fungal Infection of the Urinary Tract	p. 715
Urinary Schistosomiasis	p. 723
Urological Disorders
Nephrolithiasis and Nephrocalcinosis	p. 731
Urinary Tract Obstruction	p. 745
Urological Issues for the Nephrologist	p. 759
Tubulointerstitial Disease
Acute Interstitial Nephritis	p. 769
Vesicoureteral Reflux and Reflux Nephropathy	p. 779
Chronic Interstitial Nephritis	p. 793
Vascular Disease
Atheromatous Renovascular Disease	p. 809
Renal Vascular Thrombosis and Occlusion	p. 825
Aging and the Kidney	p. 835
Chronic Renal Failure and the Uremic Syndrome
Progression of Chronic Renal Failure	p. 843
Clinical Evaluation and Manifestations of Chronic Renal Failure	p. 857
Bone and Mineral Metabolism in Chronic Renal Failure	p. 873
Cardiovascular Disease in Chronic Renal Failure	p. 887
Anemia in Chronic Renal Failure	p. 905
Platelet Dysfunction and Coagulation Defects	p. 913
[beta]2-Microglobulin-derived Amyloid	p. 921
Acquired Cystic Kidney Disease	p. 931
Nutrition in Chronic Renal Failure	p. 935
Dialysis
Selection and Preparation of Patients for Dialysis	p. 945
Vascular Access for Hemodialysis	p. 957
Interventional Nephrology	p. 967
Hemodialysis: Mechanisms, Outcome, and Adequacy	p. 975
Acute Complications of Hemodialysis	p. 991
Peritoneal Dialysis: Principles, Techniques, and Adequacy	p. 1003
Complications of Peritoneal Dialysis	p. 1013
Other Dialysis Modalities	p. 1025
Plasma Exchange	p. 1035
Transplantation
Immunologic Principles of Kidney Transplantation	p. 1043
Immunosuppressive Agents used in Transplantation	p. 1057
Evaluation of Renal Transplant Donor and Recipient	p. 1071
Renal Transplant Surgery	p. 1083
Prophylaxis and Treatment of Renal Transplant Rejection	p. 1093
The Medical Management of the Renal Transplant Recipient	p. 1105
Chronic Transplant Rejection	p. 1125
Recurrent Disease in the Renal Transplant	p. 1135
Outcomes of Renal Transplantation	p. 1145
Pancreas and Islet Transplantation	p. 1157
Renal Disease in Liver, Cardiac, Lung, and Bone Marrow Transplantation	p. 1171
Drugs and the Kidney
Poisoning and Drug Overdose	p. 1181
Principles of Drug Dosing and Prescribing in Renal Failure	p. 1189
Index	p. 1205
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