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List of Contributors | p. ix |
Preface | p. xvii |
Dedication | p. xvii |
Essential Renal Anatomy and Physiology | |
Renal Anatomy | p. 1 |
Renal Physiology | p. 13 |
Investigation of Renal Disease | |
Assessment of Renal Function | p. 27 |
Urinalysis | p. 35 |
Imaging | p. 47 |
Renal Biopsy | p. 63 |
Fluid and Electrolyte Disorders | |
Disorders of Extracellular Volume | p. 71 |
Disorders of Water Metabolism | p. 87 |
Disorders of Potassium Metabolism | p. 109 |
Disorders of Calcium, Phosphate, and Magnesium Metabolism | p. 123 |
Normal Acid-Base Balance and Metabolic Acidosis | p. 141 |
Metabolic Alkalosis | p. 157 |
Respiratory Acidosis, Respiratory Alkalosis, and Mixed Disorders | p. 167 |
Actue Renal Failure | |
Clinical Evaluation, Management, and Outcome of Acute Renal Failure | p. 183 |
Causes of Acute Renal Failure | p. 207 |
Hepatorenal Syndrome | p. 225 |
Myeloma Kidney | p. 235 |
Glomerular Disease | |
Introduction to Glomerular Disease: Pathogenesis and Classification | p. 243 |
Introduction to Glomerular Disease: Clinical Presentations | p. 255 |
Minimal Change Disease and Primary Focal Segmental Glomerulosclerosis | p. 271 |
Secondary Focal Segmental Glomerulosclerosis | p. 283 |
Membranous Nephropathy | p. 295 |
Membranoproliferative Glomerulonephritis and Cryoglobulinemic Glomerulonephritis | p. 309 |
IgA Nephropathy and Henoch-Schonlein Nephritis | p. 319 |
Antiglomerular Basement Membrane Disease and Goodpasture's Syndrome | p. 331 |
Renal and Systemic Vasculitis | p. 341 |
Lupus Nephritis | p. 357 |
Glomerular Diseases Associated with Infection | p. 373 |
Renal Amyloidosis and Glomerular Diseases with Monoclonal Immunoglobulin Deposition | p. 387 |
Other Glomerular Disorders | p. 403 |
Thrombotic Microangiopathies including Hemolytic-Uremic Syndrome | p. 413 |
Diabetic Nephropathy | |
Clinical Manifestations and Natural History of Diabetic Nephropathy | p. 425 |
Pathogenesis, Prevention, and Treatment of Diabetic Nephropathy | p. 439 |
Management of End-stage Renal Disease in Diabetes | p. 451 |
Hypertension | |
Normal Blood Pressure Control and the Evaluation of Hypertension | p. 463 |
Pathogenesis and Clinical Course of Essential Hypertension | p. 477 |
Nonpharmacologic Treatment of Hypertension | p. 489 |
Pharmacological Treatment of Hypertension | p. 497 |
Renovascular Hypertension | p. 515 |
Endocrine Causes of Hypertension | p. 529 |
Neurogenic Hypertension Including Following Stroke and with Spinal Cord Injury | p. 543 |
Hypertension in African Americans | p. 551 |
Pregnancy and Renal Disease | |
Renal Physiology in Normal Pregnancy | p. 559 |
Complications in the Normal Pregnancy | p. 567 |
Pregnancy with Pre-Existing Renal Disease | p. 583 |
Hereditary and Congenital Diseases of the Kidney | |
Autosomal Dominant Polycystic Kidney Disease | p. 597 |
Other Cystic Kidney Diseases | p. 611 |
Alport and Other Familial Glomerular Syndromes | p. 627 |
Inherited Disorders of Sodium and Water Handling | p. 639 |
Fanconi's Syndrome and Other Proximal Tubule Disorders | p. 653 |
Sickle Cell Disease | p. 665 |
Congenital Abnormalities of the Renal Tract | p. 677 |
Urinary Tract Infection | |
Urinary Tract Infections in Adults | p. 695 |
Tuberculosis of the Urinary Tract | p. 707 |
Fungal Infection of the Urinary Tract | p. 715 |
Urinary Schistosomiasis | p. 723 |
Urological Disorders | |
Nephrolithiasis and Nephrocalcinosis | p. 731 |
Urinary Tract Obstruction | p. 745 |
Urological Issues for the Nephrologist | p. 759 |
Tubulointerstitial Disease | |
Acute Interstitial Nephritis | p. 769 |
Vesicoureteral Reflux and Reflux Nephropathy | p. 779 |
Chronic Interstitial Nephritis | p. 793 |
Vascular Disease | |
Atheromatous Renovascular Disease | p. 809 |
Renal Vascular Thrombosis and Occlusion | p. 825 |
Aging and the Kidney | p. 835 |
Chronic Renal Failure and the Uremic Syndrome | |
Progression of Chronic Renal Failure | p. 843 |
Clinical Evaluation and Manifestations of Chronic Renal Failure | p. 857 |
Bone and Mineral Metabolism in Chronic Renal Failure | p. 873 |
Cardiovascular Disease in Chronic Renal Failure | p. 887 |
Anemia in Chronic Renal Failure | p. 905 |
Platelet Dysfunction and Coagulation Defects | p. 913 |
[beta]2-Microglobulin-derived Amyloid | p. 921 |
Acquired Cystic Kidney Disease | p. 931 |
Nutrition in Chronic Renal Failure | p. 935 |
Dialysis | |
Selection and Preparation of Patients for Dialysis | p. 945 |
Vascular Access for Hemodialysis | p. 957 |
Interventional Nephrology | p. 967 |
Hemodialysis: Mechanisms, Outcome, and Adequacy | p. 975 |
Acute Complications of Hemodialysis | p. 991 |
Peritoneal Dialysis: Principles, Techniques, and Adequacy | p. 1003 |
Complications of Peritoneal Dialysis | p. 1013 |
Other Dialysis Modalities | p. 1025 |
Plasma Exchange | p. 1035 |
Transplantation | |
Immunologic Principles of Kidney Transplantation | p. 1043 |
Immunosuppressive Agents used in Transplantation | p. 1057 |
Evaluation of Renal Transplant Donor and Recipient | p. 1071 |
Renal Transplant Surgery | p. 1083 |
Prophylaxis and Treatment of Renal Transplant Rejection | p. 1093 |
The Medical Management of the Renal Transplant Recipient | p. 1105 |
Chronic Transplant Rejection | p. 1125 |
Recurrent Disease in the Renal Transplant | p. 1135 |
Outcomes of Renal Transplantation | p. 1145 |
Pancreas and Islet Transplantation | p. 1157 |
Renal Disease in Liver, Cardiac, Lung, and Bone Marrow Transplantation | p. 1171 |
Drugs and the Kidney | |
Poisoning and Drug Overdose | p. 1181 |
Principles of Drug Dosing and Prescribing in Renal Failure | p. 1189 |
Index | p. 1205 |
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