Computational Systems-Biology and Bioinformatics: First International Conference, CSBio 2010, Bangkok, Thailand, November 3-5, 2010, Proceedings

by Chan, Jonathan H.

• ISBN13: 9783642167492
• ISBN10: 3642167497
• Edition: 1st
• Format: Paperback
• Copyright: 2010-11-18
• Publisher: Springer-Verlag New York Inc

Summary

This book constitutes the refereed proceedings of the FirstInternational Conference on Computational Systems-Biology andBioinformatics, CSBio 2010, held in Bangkok, Thailand, in November 2010.The 19 revised full papers presented were carefully reviewed andselected from a total of 48 submissions. The papers cover a wide rangeof topics and are organized in five topical sections on modeling andsimulation of biological processes, gene expression analysis, biologicalsequence analysis and network reconstruction, bio-data visualization andbiological databases, as well as medical and biomedical informatics.

Table of Contents

Modeling and Simulation of Biological Processes
A Formal Model for Gene Regulatory Networks with Time Delays	p. 1
Modelling fim Expression in Escherichia Coli K12	p. 14
Study of the Structural Pathology Caused by CYP2C9 Polymorphisms Towards Flurbiprofen Metabolism Using Molecular Dynamics Simulation	p. 26
3D Structure Modeling of a Transmembrane Protein, Fatty Acid Elongase	p. 36
Gene Expression Analysis
Sequential Application of Feature Selection and Extraction for Predicting Breast Cancer Aggressiveness	p. 46
On Assigning Individuals from Cryptic Population Structures to Optimal Predicted Subpopulations: An Empirical Evaluation of Non-parametric Population Structure Analysis Techniques	p. 58
Extended Constraint-Based Boolean Analysis: A Computational Method in Genetic Network Inference	p. 71
Mining LINE-1 Characteristics That Mediate Gene Expression	p. 83
Biological Sequence Analysis and Network Reconstruction
Mining Regulatory Elements in Non-coding Regions of Arabidopsis Thaliana	p. 94
Prediction of Non-coding RNA and Their Targets in Spirulina Platensis Genome	p. 106
Reconstruction of Starch Biosynthesis Pathway in Cassava Using Comparative Genomic Approach	p. 118
Bio-data Visualization and Biological Databases
Catalog of Genetic Variations (SNPs and CNVs) and Analysis Tools for Thai Genetic Studies	p. 130
The Genome Atlas Resource	p. 141
INVERTER: INtegrated Variable numbER Tandem rEpeat findeR	p. 151
Design of an Enterobacteriaceae Pan-Genome Microarray Chip	p. 165
Medical and Biomedical Informatics
Multi-objective Particle Swarm Optimisation for Phase Specific Cancer Drug Scheduling	p. 180
A Vaccine Strategy for Plant Allergy by RNA Interference - An in Silico Approach	p. 193
Unsupervised Algorithms for Population Classification and Ancestry Informative Marker Selection	p. 208
Genome-Based Screening for Drug Targets Identification: Application to Typhoid Fever	p. 217
Author Index	p. 227
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