Coronary Thrombosis in Perspective

by Sobel, Burton E.; Collen, Desire

• ISBN13: 9780824791544
• ISBN10: 0824791541
• Format: Hardcover
• Copyright: 1993-08-01
• Publisher: Marcel Dekker Inc

Table of Contents

Series Introduction
Preface
Contributors
Coronary Thrombolysis: Background and Factors Underlying Its Emergence	p. 1
Thrombolytic Agents	p. 11
The Nature of Atherosclerotic Lesions Giving Rise to Acute Coronary Thrombosis	p. 35
The Objectives of Coronary Thrombolysis	p. 53
The Impact of Time to Treatment on the Efficacy of Coronary Thrombolysis	p. 65
Procoagulant Effects of Fibrinolytic Agents	p. 77
The Role of Platelets in Thrombolysis, Thrombosis, and Thrombolytic Therapy	p. 101
Relationships Between Suppression of Coagulation and Prevention of Reocclusion	p. 123
Strengths and Limitations of Specific Antithrombotic Regimens and Agents	p. 143
Discrepancies Between End-Point Results in Clinical Trials of Thrombolytic Therapy: The Salvage Paradigm Revisited	p. 167
Coronary Artery Patency	p. 183
Mortality as an End Point in Studies of Coronary Thrombolysis	p. 193
Clinical Factors Militating Against Sustained Patency and Their Consequences	p. 221
Efficacy of Currently Available Conjunctive Regimens	p. 255
Myocardial Reperfusion Injury: Concepts, Mechanisms, and Therapeutic Strategies	p. 271
Epilogue. Controversy and Clarification: Preliminary Results of the GUSTO Trial	p. 303
Index	p. 317
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