Coronaviruses with Special Emphasis on First Insights Concerning SARS

by Schmidt, Axel; Wolff, Manfred P. H.; Weber, Olaf F.

• ISBN13: 9783764364625
• ISBN10: 3764364629
• Format: Hardcover
• Copyright: 2005-04-30
• Publisher: Birkhauser

Summary

The outbreak of SARS (Severe acute respiratory syndrome), an atypical pneumonia, has received much attention and coverage by the media and has consequently had a high impact on the public. The infectivity and route of transmission of the disease appear unusual, and it turned out to be a highly relevant threat for medical staff. This monograph provides comprehensive information on the newest insights into the SARS epidemic and the responsible infectious agent. Background information on Coronaviridae (coronavirus/torovirus) and coronavirus/torovirus-associated infections in humans and animals is also given. The volume will be a valuable source of information for researchers and clinicians in virology, epidemiology and biomedicine.

Table of Contents

List of contributors	vii
Glossary	xi
Preface	xiii
Dave Cavanagh
Coronaviridae: a review of coronaviruses and toroviruses	1	(54)
Olaf Weber and Axel Schmidt
Coronavirus infections in veterinary medicine	55	(16)
Princess Margaret Hospital SARS Study Group: Po Oi Lee, Ping Tim Tsui, Tak Yin Tsang, Tai Nin Chau, Chi Pong Kwan, Wai Cho Yu and Sik To Lai
Severe acute respiratory syndrome: clinical features	71	(16)
Sherif R. Zaki and Cynthia S. Goldsmith
SARS coronavirus infection: pathology and pathogenesis of an emerging virus disease	87	(14)
Caroline R. Astell, Steven J.M. Jones, Robert A. Holt and Marco A. Marra
Genome organization and structural aspects of the SARS-related virus	101	(28)
Wolfgang Preiser, Christian Drosten and Hans Wilhelm Doerr
Virological laboratory diagnosis of SARS	129	(16)
Charlene E. Bush-Donovan, Tony Mazzulli, Jill J. Detmer and Johan Surtihadi
Performance evaluation of a Bayer Healthcare Diagnostics research-based SARS-coronavirus assay	145	(14)
Arthur Chun-Wing Lau, Loletta Kit-Ying So and Loretta Yin-Chun Yam
Current status of therapy of SARS	159	(14)
Kanchan Anand, Haitao Yang, Zihe Rao and Rolf Hilgenfeld
Coronavirus main proteinase: target for antiviral drug therapy	173	(28)
Manfred H. Wolff Syed A. Sattar, Olusola Adegbunrin and Jason Tetro
Environmental survival and mircobicide inactivation of coronaviruses	201	(12)
Andrea Ammon
Disease management strategies in SARS	213	(14)
Index	227