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9781872748740

Cortical Plasticity LTP and LTD

by ;
  • ISBN13:

    9781872748740

  • ISBN10:

    1872748740

  • Edition: 1st
  • Format: Hardcover
  • Copyright: 1998-02-12
  • Publisher: Oxford University Press
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Supplemental Materials

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Summary

Understanding the mechanisms of learning and memory provides one of the major challenges of contemporary neuroscience. At the reductionist level this equates to an understanding of synaptic plasticity within cortical structures such as the hippocampus. Recently, considerable effort has been devoted to researching two forms of associative synaptic plasticity: long-term potentiation (LTP) and its counterpart, long-term depression (LTD). Increasingly, this field is being influenced by molecular approaches, and Cortical Plasticity brings together the recent findings on all aspects of the induction, maintenance, and expression of LTP and LTD, with an emphasis on molecular mechanisms. This book provides an invaluable overview of a rapidly expanding field and presents discussions from internationally known researchers on a number of controversial issues regarding synaptic plasticity. It will be essential reading for researchers in all areas of neuroscience.

Table of Contents

Introduction and Overview
The Role of Amino Acid Receptors in Synaptic Plasticity
Second Messengers in LTP and LTD
The Locus of Expression of NMDA Receptor-Dependent LTP in the Hippocampus
Post-Translational Mechanisms Which Could Underlie the Postsynaptic Expression of LTP and LTD
Postsynaptic Gene Expression and Long-Term Potentiation in the Hippocampus
Neuromodulators of Synaptic Strength
Epileptogenesis
Bidirectional Plasticity of Cortical Synapses
Synaptic Plasticity in the Cerebellum
Roles of LTP and LTD in Neuronal Network Operations in the Brain
Table of Contents provided by Publisher. All Rights Reserved.

Supplemental Materials

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