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9780226767826

Creating a Physical Biology

by ;
  • ISBN13:

    9780226767826

  • ISBN10:

    0226767825

  • Format: Hardcover
  • Copyright: 2011-12-15
  • Publisher: Univ of Chicago Pr

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Summary

In 1935 geneticist Nikolai Timof eff-Ressovsky, radiation physicist Karl G. Zimmer, and quantum physicist Max Delbr ck published “On the Nature of Gene Mutation and Gene Structure,” known subsequently as the “Three-Man Paper.” This seminal paper advanced work on the physical exploration of the structure of the gene through radiation physics and suggested ways in which physics could reveal definite information about gene structure, mutation, and action. Representing a new level of collaboration between physics and biology, it played an important role in the birth of the new field of molecular biology. The paper’s results were popularized for a wide audience in the What is Life?lectures of physicist Erwin Schr dinger in 1944. Despite its historical impact on the biological sciences, the paper has remained largely inaccessible because it was only published in a short-lived German periodical. Creating a Physical Biologymakes the Three Man Paper available in English for the first time. Brandon Fogel’s translation is accompanied by an introductory essay by Fogel and Phillip Sloan and a set of essays by leading historians and philosophers of biology that explore the context, contents, and subsequent influence of the paper, as well as its importance for the wider philosophical analysis of biological reductionism.

Table of Contents

Prefacep. vii
Introductionp. 1
Historical Origins of the Three-Man Paper
Physics and Genes: From Einstein to Delbrückp. 39
Biophysics in Berlin: The Delbrück Clubp. 61
Exhuming the Three-Man Paper: Target-Theoretical Research in the 1930s and 1940sp. 99
Philosophical Perspectives on the Three-Man Paper
Niels Bohr and Max Delbrück: Balancing Autonomy and Reductionism in Biologyp. 145
Was Delbrück a Reductionist?p. 179
The Three-Man Paper
Translator's Prefacep. 213
The Text of the Three-Man Paperp. 221
References in the Three-Man Paperp. 272
Combined Bibliographyp. 281
List of Contributorsp. 307
Indexp. 309
Table of Contents provided by Ingram. All Rights Reserved.

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